Abstract：
Concerns have been conveyed regarding the availability and hazards of microplastics (MPs) in aquatic biota due to their widespread presence in aquatic habitats. Zebrafish (Danio rerio) are widely used as a model organism to study the adverse impacts of MPs due to their several compelling advantages, such as their small size, ease of breeding, inexpensive maintenance, short life cycle, year-round spawning, high fecundity, fewer legal restrictions, and genetic resemblances to humans. Exposure of organisms to MPs produces physical and chemical toxic effects, including abnormal behavior, oxidative stress, neurotoxicity, genotoxicity, immune toxicity, reproductive imbalance, and histopathological effects. But the severity of the effects is size and concentration-dependent. It has been demonstrated that smaller particles could reach the gut and liver, while larger particles are only confined to the gill, the digestive tract of adult zebrafish. This thorough review encapsulates the current body of literature concerning research on MPs in zebrafish and demonstrates an overview of MPs size and concentration effects on the physiological, morphological, and behavioral characteristics of zebrafish. Finding gaps in the literature paves the way for further investigation.
摘要：
由于微塑料（MP）在水生生物中的广泛存在，因此人们对它们在水生生物中的可用性和危害表示关注。斑马鱼（Daniorerio）被广泛用作模型生物来研究MP的不利影响，因为它们具有几个令人信服的优势，比如它们的小尺寸，易于繁殖，廉价的维护，短生命周期,全年产卵，高繁殖力，更少的法律限制，和人类的基因相似。生物体暴露于MP会产生物理和化学毒性作用，包括异常行为,氧化应激，神经毒性，遗传毒性，免疫毒性，生殖不平衡，和组织病理学影响。但是影响的严重程度取决于大小和浓度。已经证明，较小的颗粒可以到达肠道和肝脏，虽然较大的颗粒只局限于g，成年斑马鱼的消化道。这篇全面的综述囊括了当前关于斑马鱼中MPs研究的文献，并展示了MPs大小和浓度对其生理效应的概述，形态学,和斑马鱼的行为特征。发现文献中的空白为进一步调查铺平了道路。
