Abstract：
OBJECTIVE: To investigate the clinical efficacy and prognostic factors associated with autologous osteoperiosteal transplantation for the treatment of single cystic osteochondral lesions of the talus (OLT).
METHODS: The clinical data of patients with single cystic OLT undergoing autologous osteoperiosteal transplantation at the Department of Foot and Ankle Surgery of our hospital between 2018 and 2022, including complete follow-up, were retrospectively analyzed. Imaging data from each patient were imported into Mimics software to measure the surface area, volume and depth of the lesions. Then, the talus nine-compartment partitioning method was used to partition the injury site. Preoperative and final follow-up assessments were performed using the American Orthopaedic Foot and Ankle Society (AOFAS) score, visual analogue scale (VAS) for pain and 36-item Short-Form Health Survey (SF-36) to evaluate treatment efficacy and analyze prognostic factors.
RESULTS: Of the 31 patients with single cystic OLT with a complete set of follow-up data, there were 17 males and 14 females, with a mean age of 43.3 ± 13.6 years, a mean follow-up time of 30.1 ± 14.0 months and a mean illness duration of 30.4 ± 20.0 months. The postoperative final follow-up AOFAS score was 90.7 ± 5.5; this represented significant improvement when compared to the preoperative score of 57.0 ± 8.5 (P < 0.001). The final postoperative follow-up VAS score was 18.5 ± 8.3; this was significantly better than the preoperative score of 57.8 ± 8.7 (P < 0.001). The physical component summary (PCS) score and mental component summary (MCS) score on the SF-36 scale showed significant improvement at the final postoperative follow-up when compared to preoperative scores (p < 0.001). No other complications were observed during follow-up, such as wound infection or pain at the donor site. One of the patients showed less improvement, which may be related to premature weight-bearing or re-sprained ankle after surgery. There was no significant correlation between the duration of illness, gender and the location, depth, surface area and volume of the OLT and the postoperative scores. However, patient age showed a significant negative correlation with the postoperative SF-36 PCS and MCS scores.
CONCLUSIONS: Autologous osteoperiosteal transplantation for single cystic OLT demonstrated good clinical efficacy with a low incidence of complications. Furthermore, age represents an important factor influencing prognosis.
METHODS: Level II.
METHODS: The clinical data of patients with single cystic OLT undergoing autologous osteoperiosteal transplantation at the Department of Foot and Ankle Surgery of our hospital between 2018 and 2022, including complete follow-up, were retrospectively analyzed. Imaging data from each patient were imported into Mimics software to measure the surface area, volume and depth of the lesions. Then, the talus nine-compartment partitioning method was used to partition the injury site. Preoperative and final follow-up assessments were performed using the American Orthopaedic Foot and Ankle Society (AOFAS) score, visual analogue scale (VAS) for pain and 36-item Short-Form Health Survey (SF-36) to evaluate treatment efficacy and analyze prognostic factors.
RESULTS: Of the 31 patients with single cystic OLT with a complete set of follow-up data, there were 17 males and 14 females, with a mean age of 43.3 ± 13.6 years, a mean follow-up time of 30.1 ± 14.0 months and a mean illness duration of 30.4 ± 20.0 months. The postoperative final follow-up AOFAS score was 90.7 ± 5.5; this represented significant improvement when compared to the preoperative score of 57.0 ± 8.5 (P < 0.001). The final postoperative follow-up VAS score was 18.5 ± 8.3; this was significantly better than the preoperative score of 57.8 ± 8.7 (P < 0.001). The physical component summary (PCS) score and mental component summary (MCS) score on the SF-36 scale showed significant improvement at the final postoperative follow-up when compared to preoperative scores (p < 0.001). No other complications were observed during follow-up, such as wound infection or pain at the donor site. One of the patients showed less improvement, which may be related to premature weight-bearing or re-sprained ankle after surgery. There was no significant correlation between the duration of illness, gender and the location, depth, surface area and volume of the OLT and the postoperative scores. However, patient age showed a significant negative correlation with the postoperative SF-36 PCS and MCS scores.
CONCLUSIONS: Autologous osteoperiosteal transplantation for single cystic OLT demonstrated good clinical efficacy with a low incidence of complications. Furthermore, age represents an important factor influencing prognosis.
METHODS: Level II.
摘要：
目的：探讨自体骨膜骨膜移植治疗单囊性距骨软骨病(OLT)的临床疗效及影响预后的相关因素。
方法：2018年至2022年在我院足踝外科接受自体骨膜骨膜移植的单囊OLT患者的临床资料，包括完整的随访，进行回顾性分析。将每位患者的影像数据导入Mimics软件以测量表面积，病变的体积和深度。然后，采用距骨九室分割方法对损伤部位进行分割。使用美国骨科足踝协会（AOFAS）评分进行术前和最终随访评估，疼痛视觉模拟评分（VAS）和36项短期健康调查（SF-36）评估治疗效果并分析预后因素。
结果：在31例单囊性OLT患者中，有一套完整的随访数据，有17名男性和14名女性，平均年龄为43.3±13.6岁，平均随访时间为30.1±14.0个月，平均病程为30.4±20.0个月。术后最终随访AOFAS评分为90.7±5.5；与术前评分57.0±8.5相比，显着改善（P<0.001）。术后末次随访VAS评分为18.5±8.3,明显优于术前评分57.8±8.7(P<0.001)。SF-36量表的物理成分汇总（PCS）评分和心理成分汇总（MCS）评分与术前评分相比，在最终的术后随访中显示出显着改善（p<0.001）。随访期间未观察到其他并发症,如伤口感染或供体部位疼痛。其中一名患者改善较少，这可能与手术后过早负重或踝关节再扭伤有关。病程之间没有显著的相关性,性别和位置，深度,OLT的表面积和体积以及术后评分。然而,患者年龄与术后SF-36PCS和MCS评分呈显著负相关.
结论：自体骨膜移植治疗单囊性OLT临床疗效好，并发症发生率低。此外，年龄是影响预后的重要因素。
方法：二级。
方法：2018年至2022年在我院足踝外科接受自体骨膜骨膜移植的单囊OLT患者的临床资料，包括完整的随访，进行回顾性分析。将每位患者的影像数据导入Mimics软件以测量表面积，病变的体积和深度。然后，采用距骨九室分割方法对损伤部位进行分割。使用美国骨科足踝协会（AOFAS）评分进行术前和最终随访评估，疼痛视觉模拟评分（VAS）和36项短期健康调查（SF-36）评估治疗效果并分析预后因素。
结果：在31例单囊性OLT患者中，有一套完整的随访数据，有17名男性和14名女性，平均年龄为43.3±13.6岁，平均随访时间为30.1±14.0个月，平均病程为30.4±20.0个月。术后最终随访AOFAS评分为90.7±5.5；与术前评分57.0±8.5相比，显着改善（P<0.001）。术后末次随访VAS评分为18.5±8.3,明显优于术前评分57.8±8.7(P<0.001)。SF-36量表的物理成分汇总（PCS）评分和心理成分汇总（MCS）评分与术前评分相比，在最终的术后随访中显示出显着改善（p<0.001）。随访期间未观察到其他并发症,如伤口感染或供体部位疼痛。其中一名患者改善较少，这可能与手术后过早负重或踝关节再扭伤有关。病程之间没有显著的相关性,性别和位置，深度,OLT的表面积和体积以及术后评分。然而,患者年龄与术后SF-36PCS和MCS评分呈显著负相关.
结论：自体骨膜移植治疗单囊性OLT临床疗效好，并发症发生率低。此外，年龄是影响预后的重要因素。
方法：二级。
