METHODS: A retrospective review was conducted at a single center, encompassing 36 NF1 patients with giant neurofibromas in the extremities and trunk wall who underwent debulking surgery from July 2010 to July 2022.
RESULTS: Twenty-one male and fifteen female NF1 patients who received one to four surgical interventions were evaluated. The average age at the time of surgery was 17.8 years. The median follow-up time was 52 months. Our findings revealed relatively low rates of complications and recurrence. Notably, patients expressed satisfaction with both the aesthetic and functional results.
CONCLUSIONS: Debulking surgery of giant neurofibromas in the extremities and trunk wall of NF1 patients can effectively reduce the tumor burden, leading to improvements in both the appearance and function.
方法:在单个中心进行了回顾性审查,2010年7月至2022年7月,纳入36例NF1四肢和躯干壁巨大神经纤维瘤患者。
结果:对21名男性和15名女性NF1患者进行了评估,这些患者接受了1至4次手术干预。手术时的平均年龄为17.8岁。中位随访时间为52个月。我们的发现显示并发症和复发率相对较低。值得注意的是,患者对美学和功能结果表示满意。
结论:NF1患者四肢和躯干壁巨大神经纤维瘤的膨化手术可有效减轻肿瘤负担,导致外观和功能的改进。