关键词: monkeypox monkeypox virus mpox orthopoxvirus poxvirus zoonotic disease

来  源:   DOI:10.1002/hsr2.2136   PDF(Pubmed)

Abstract:
UNASSIGNED: A double-stranded DNA virus called monkeypox virus (MPV) belonging to the Poxviridae family and Orthopoxvirus genus causes monkeypox (mpox) infection. This virus used to infect only Central, East, and West Africa. However, it has spread to an extent outside Africa recently. The range of MPV outbreaks was so high that on July 23, 2022, the World Health Organization (WHO) declared it a Public Health Emergency of International Concern (PHEIC). About a year later, the WHO notified the end of a global public health emergency for mpox on May 11, 2023. Here, we aimed to assess the current pathogenicity and potential risk of MPV causing public health emergencies.
UNASSIGNED: We searched information from published articles available in PubMed, Scopus, and ScienceDirect. We used monkeypox, mpox, monkeypox outbreak, and monkeypox virus as keywords during the literature search.
UNASSIGNED: Many new variants of MPV have emerged throughout the world that created PHEIC for mpox. Considering the low lethality and transmission rate, mpox is no longer a global public health threat. In addition, the availability of therapeutic and preventive measures helped the healthcare authorities fight the mpox infection in an efficient manner. In this review, we have portrayed the history and evolution of mpox from past to present and an idea of its future outcomes. Also, we have discussed the symptoms related to mpox and approved antiviral treatment strategies to fight off the infection in this piece. This review also emphasized the preventive guidelines set by the WHO for patients, caregivers, and healthcare providers to control the outbreak of mpox infection.
UNASSIGNED: We believe this article would give an idea about the potential public health threats of the recent multi-country monkeypox outbreak to the healthcare authorities for taking measures accordingly.
摘要:
一种称为猴痘病毒(MPV)的双链DNA病毒,属于Poxviridae家族和正痘病毒属,可引起猴痘病毒(mpox)感染。这种病毒过去只感染中央,东,和西非。然而,它最近已经蔓延到非洲以外的地方。MPV爆发的范围如此之高,以至于2022年7月23日,世界卫生组织(WHO)宣布这是国际关注的突发公共卫生事件(PHEIC)。大约一年后,世卫组织于2023年5月11日通知全球突发公共卫生事件结束。这里,我们旨在评估MPV引起突发公共卫生事件的当前致病性和潜在风险.
我们从PubMed上发表的文章中搜索了信息,Scopus,和科学直接。我们用猴痘,水痘,猴痘爆发,并以猴痘病毒为关键词进行文献检索。
许多新的MPV变种已经出现在世界各地,它们为mpox创造了PHEIC。考虑到低杀伤力和传播率,水痘不再是全球公共卫生威胁。此外,治疗和预防措施的可用性帮助医疗保健当局以有效的方式对抗水痘感染。在这次审查中,我们描绘了从过去到现在的历史和演变,以及对未来结果的看法。此外,在这篇文章中,我们已经讨论了与水痘相关的症状,并批准了抗病毒治疗策略来抵御感染。这篇综述还强调了世卫组织为患者制定的预防指南,看护者,和医疗保健提供者控制水痘感染的爆发。
我们相信本文将向医疗当局提供有关最近多国猴痘爆发的潜在公共卫生威胁的想法,以采取相应措施。
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