关键词: Antibiotics Hand surgery Infection Quality improvement Surgical prophylaxis

来  源:   DOI:10.1016/j.jhsg.2024.01.013   PDF(Pubmed)

Abstract:
UNASSIGNED: Although data support foregoing preoperative antibiotics for outpatient, soft-tissue procedures, there is a paucity of evidence regarding antibiotics for implant-based hand procedures. The purpose of this investigation was to assess early postoperative infectious concerns for patients undergoing implant-based hand surgery, regardless of preoperative antibiotic use.
UNASSIGNED: A retrospective cohort analysis was performed consisting of all patients undergoing implant-based hand procedures between January 2015 and October 2021. Primary outcomes included antibiotic prescription or reoperation for infection within 90 days of surgery. Demographics (age, gender, body mass index, diabetes, and smoking status) and hand surgery procedure type were recorded. To account for differences in baseline characteristics between patients who did and did not receive preoperative antibiotics, covariate balancing was performed with subsequent weighted logistic regression models constructed to estimate the effect of no receipt of preoperative antibiotics on the need for postoperative antibiotics. In a separate logistic regression analysis, patients\' baseline characteristics were evaluated together as predictors of postoperative antibiotic prescription.
UNASSIGNED: One thousand eight hundred sixty-two unique procedures were reviewed with 1,394 meeting criteria. Two hundred thirty-six patients (16.9%) were not prescribed preoperative antibiotics. Overall, 54 (3.87%) and 69 (4.95%) patients received antibiotics within 30 and 90 days of surgery, respectively. One patient (0.07%) underwent reoperation. There were no differences in the rates of 30- and 90-day postoperative antibiotic prescriptions between the two groups. After covariant balancing of risk factors, patients not prescribed preoperative antibiotics did not display significantly higher odds of requiring postoperative antibiotics at 30 or 90 days. Logistic regression models showed male gender, temporary Kirschner wire fixation, and elevated body mass index were associated with increased postoperative antibiotics at 30 and 90 days.
UNASSIGNED: For implant-based hand procedures, there was no increased risk in postoperative antibiotic prescription or reoperation for patients who did not receive preoperative antibiotics.
UNASSIGNED: Therapeutic III.
摘要:
尽管数据支持在门诊使用术前抗生素,软组织手术,缺乏关于用于植入手部手术的抗生素的证据.这项调查的目的是评估接受植入手外科手术的患者术后早期感染问题,无论术前使用抗生素。
对2015年1月至2021年10月期间接受植入手部手术的所有患者进行了回顾性队列分析。主要结果包括抗生素处方或手术后90天内感染的再次手术。人口统计(年龄,性别,身体质量指数,糖尿病,和吸烟状况)和手外科手术类型被记录。为了解释接受和未接受术前抗生素治疗的患者之间基线特征的差异,使用随后构建的加权逻辑回归模型进行协变量平衡,以评估术前未接受抗生素对术后抗生素需求的影响.在单独的逻辑回归分析中,患者的基线特征作为术后抗生素处方的预测因子进行评估.
审查了一千八百六十二个独特的程序,符合1,394项标准。136例患者(16.9%)未开术前抗生素。总的来说,54例(3.87%)和69例(4.95%)患者在手术后30天和90天内接受抗生素治疗,分别。1例(0.07%)再次手术。两组术后30天和90天的抗生素处方率没有差异。在风险因素的协变平衡之后,未使用术前抗生素的患者在术后30天或90天时需要使用抗生素的几率没有显著升高.Logistic回归模型显示男性性别,临时克氏针固定,体重指数升高与术后30天和90天的抗生素增加相关。
对于基于植入物的手部手术,对于未接受术前抗生素治疗的患者,术后抗生素处方或再次手术的风险没有增加.
治疗III.
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