PDF(Pubmed)
Abstract：
Moyamoya disease (MMD) is a rare, idiopathic, progressive, obstructive, vasculopathy affecting primarily the terminal portions of the intracerebral internal carotid arteries, typically at the base of the brain. It is more commonly seen in people of East Asian descent. The moyamoya phenomenon refers to the characteristic appearance of the tangle of fine blood vessels, also described as a puff of smoke. Moyamoya syndrome (MMS) refers to the constriction-induced chronic brain ischemia that is believed to cause overexpression of proangiogenic factors, creating a fragile network of collateral capillaries. MMS refers to the moyamoya phenomenon in the presence of other congenital or acquired disorders. Intracerebral hemorrhage is the leading cause of death for MMS patients. Overall, the prognosis is variable. Cardiac myxoma can cause embolization of tumor cells, plaques, and thrombus, and recurrent thromboembolism can lead to chronic brain ischemia, which can lead to the development of collaterals. There have been cases reported where the moyamoya phenomenon resolved following myxoma resection. Here, we present the case of a female who had intraventricular bleeding and was diagnosed with MMD. Eighteen months later, she presented with shortness of breath and was diagnosed with cardiac myxoma with multiple valvular regurgitations. The myxoma was surgically removed.
摘要：
烟雾病（MMD）是一种罕见的，特发性,进步,阻塞性,血管病变主要影响脑内颈内动脉的末端部分，通常在大脑的底部。在东亚血统的人中更常见。烟雾现象是指细血管缠结的特征外观，也被描述为一股烟。烟雾综合征（MMS）是指狭窄引起的慢性脑缺血，被认为会导致促血管生成因子的过度表达，形成了一个脆弱的附属毛细血管网络.MMS是指存在其他先天性或获得性疾病的烟雾现象。脑出血是MMS患者死亡的主要原因。总的来说,预后是可变的。心脏粘液瘤可引起肿瘤细胞栓塞，斑块,和血栓，反复的血栓栓塞会导致慢性脑缺血,这可能导致抵押品的发展。有报道称，粘液瘤切除术后烟雾现象得到解决。这里,我们介绍了一例女性,她有脑室内出血,并被诊断为MMD.十八个月后,她出现呼吸急促，被诊断为心脏黏液瘤伴多个瓣膜反流。粘液瘤被手术切除。
