关键词: acantholysis desmoglein 1 pemphigus erythematosus pemphigus foliaceus seborrheic pemphigus

来  源:   DOI:10.7759/cureus.59389   PDF(Pubmed)

Abstract:
Seborrheic pemphigus (SP) represents a localized and superficial form of pemphigus foliaceus (PF) often mistaken for other dermatological conditions such as seborrheic dermatitis (SD) due to clinical similarities. Additionally, SP may be conceptually confused with pemphigus erythematosus (PE) due to historical terminology and overlapping clinical features. We present a case study of a 38-year-old female initially diagnosed with SD but later identified as SP through detailed clinical and histopathological analysis. We discuss the challenges in accurately diagnosing SP, emphasizing the importance of distinguishing it from PE and other acantholytic dermatoses. Furthermore, we highlight the effectiveness of topical treatment in managing SP, contrary to the systemic therapy often required for PE. Our findings underscore the necessity for further research to optimize management strategies for SP and emphasize the significance of precise terminology in clinical practice and research.
摘要:
脂溢性天疱疮(SP)代表了天疱疮(PF)的局部和表面形式,由于临床相似性,通常被误认为是其他皮肤病,例如脂溢性皮炎(SD)。此外,由于历史术语和重叠的临床特征,SP可能在概念上与红斑天疱疮(PE)混淆。我们提供了一个案例研究,该案例研究是一名38岁的女性,最初被诊断为SD,但后来通过详细的临床和组织病理学分析确定为SP。我们讨论了准确诊断SP的挑战,强调将其与PE和其他棘皮松解性皮肤病区分开的重要性。此外,我们强调了局部治疗在管理SP方面的有效性,与PE通常需要的全身治疗相反。我们的发现强调了进一步研究以优化SP管理策略的必要性,并强调了精确术语在临床实践和研究中的重要性。
公众号