关键词: chemotherapy growing teratoma syndrome non-seminomatous germ cell tumor pulmonary metastasis retroperitoneal mass surgical excision

来  源:   DOI:10.7759/cureus.59335   PDF(Pubmed)

Abstract:
Growing teratoma syndrome (GTS) represents a rare yet significant complication following treatment for non-seminomatous germ cell tumors (NSGCT), characterized by the growth of mature teratoma elements despite prior chemotherapy. We present the case of a 30-year-old male who, following orchidectomy for NSGCT and subsequent chemotherapy, developed acute abdominal pain and pulmonary metastasis. Despite normal serum tumor markers, imaging revealed a large retroperitoneal mass encasing significant vessels. Surgical excision led to symptom resolution. This case underscores the diagnostic challenges GTS poses, the importance of imaging in diagnosis, and the efficacy of prompt surgical intervention in achieving favorable outcomes.
摘要:
生长畸胎瘤综合征(GTS)是治疗非精原细胞生殖细胞肿瘤(NSGCT)后一种罕见但显著的并发症,尽管事先化疗,其特征是成熟畸胎瘤元素的生长。我们介绍一个30岁的男性,NSGCT的睾丸切除术和随后的化疗后,出现急性腹痛和肺转移。尽管血清肿瘤标志物正常,影像学显示一个大的腹膜后肿块包裹着重要的血管。手术切除导致症状缓解。这个案例强调了GTS带来的诊断挑战,成像在诊断中的重要性,以及及时手术干预在实现有利结果方面的功效。
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