PDF(Pubmed)
Abstract：
Rhabdomyolysis, a medical condition caused by the destruction of striated muscle fibers, can have many etiologies, with the most common one being traumatic etiologies, that is, crushing injuries, heavy exertion, and being trapped under rubbles, and so forth. Rhabdomyolysis causes many complications, including acute kidney injury and different electrolyte imbalances, which later can cause cardiac dysrhythmia and even death as a result. This systematic review and meta-analysis investigate the incidence of imbalances of four important electrolytes among patients diagnosed with traumatic rhabdomyolysis. PubMed, Scopus, Web of Science, and Embase databases were searched for any article related to traumatic rhabdomyolysis using keywords related to the topic of our study, excluding case studies and case series. Relevant data were extracted from the included articles, and finally, a meta-analysis was performed on them to calculate the pooled incidence of each electrolyte imbalance. Collectively, 32 articles were included in our study (through the database and citation checking). The following were the pooled incidence of each electrolyte imbalance: hyperkalemia, 31% (95%CI 22%-41%); hypokalemia, 10% (95%CI 4%-17%); hypernatremia, 3% (95%CI 0%-8%); hyponatremia, 23% (95%CI 7%-44%); hypercalcemia, 0% (95%CI 0%-1%); hypocalcemia, 57% (95%CI: 22%-88%); hyperphosphatemia, 33% (95%CI 11%-59%); hypophosphatemia, 4% (95%CI 0%-16%). According to the meta-analyses, the rate of hyperkalemia, hyponatremia, hypocalcemia, and hyperphosphatemia is higher than their counterpart in patients diagnosed with traumatic rhabdomyolysis.
摘要：
横纹肌溶解症,由横纹肌纤维破坏引起的医疗状况，可以有许多病因，最常见的是创伤性病因，也就是说,压伤,剧烈运动,被困在瓦砾下，等等。横纹肌溶解导致许多并发症，包括急性肾损伤和不同的电解质失衡，这后来会导致心律失常甚至死亡。本系统综述和荟萃分析调查了外伤性横纹肌溶解症患者中四种重要电解质失衡的发生率。PubMed,Scopus,WebofScience,和Embase数据库使用与我们研究主题相关的关键词搜索任何与创伤性横纹肌溶解相关的文章，不包括案例研究和案例系列。从收录的文章中提取相关数据，最后，我们对它们进行了荟萃分析,以计算每种电解质失衡的汇总发生率.总的来说，32篇文章被纳入我们的研究(通过数据库和引文检查)。以下是每种电解质失衡的汇总发生率：高钾血症，31%（95CI22%-41%）；低钾血症，10%（95CI4%-17%）；高钠血症，3%（95CI0%-8%）；低钠血症，23%（95CI7%-44%）；高钙血症，0%（95CI0%-1%）；低钙血症，57%（95CI：22%-88%）；高磷血症，33%（95CI11%-59%）；低磷酸盐血症，4%（95CI0%-16%）。根据荟萃分析，高钾血症的发生率,低钠血症,低钙血症,在诊断为外伤性横纹肌溶解症的患者中，高磷血症高于高磷血症。
