PDF(Pubmed)
Abstract：
A full-term male neonate presented on the 11th day of life with late-onset multisystem inflammatory syndrome-neonate (MIS-N) (cardioneurological compromise). Immediate anti-inflammatory modulation led to a gradual recovery of neurological and coronary lesions. However, temporal evaluation unmasked silent myocardial dysfunction in echocardiography validated further by elevated biomarkers, myocardial fibrosis in cardiac magnetic resonance imaging, and abnormal strain study persisting till 16 months of follow-up. This revealed a hitherto unknown and rare progression of MIS-N into dilated cardiomyopathy.
摘要：
一名足月男性新生儿在生命的第11天出现迟发性多系统炎症综合征-新生儿（MIS-N）（心脏神经学妥协）。立即抗炎调节导致神经和冠状动脉病变的逐渐恢复。然而,超声心动图的时间评估未掩盖的无症状心肌功能障碍，通过升高的生物标志物进一步验证，心脏磁共振成像中的心肌纤维化，异常菌株研究持续到16个月的随访。这揭示了MIS-N迄今为止未知且罕见的进展为扩张型心肌病。
