关键词: Malignancy Malignant melanotic schwannoma Malignant tumors of the central nervous system Spinal tumors

Mesh : Humans Female Adult Spinal Cord Neoplasms / pathology surgery diagnosis Neurilemmoma / pathology diagnosis surgery Cervical Cord / pathology diagnostic imaging Cervical Vertebrae / pathology surgery

来  源:   DOI:10.1186/s12883-024-03686-0   PDF(Pubmed)

Abstract:
Spinal cord malignant melanotic schwannoma (MMNST) is a rare central nervous system tumor that originates from the spinal cord or spinal myelin sheath cells and can produce melanin. This type of tumor is usually highly aggressive and malignant, with a poor prognosis. The clinical manifestations of spinal cord MMNST are mainly pain, paresthesia, muscle weakness, muscle atrophy, etc., and symptoms of spinal cord compression, such as intestinal and bladder dysfunction, paraplegia, etc. Early detection of tumor lesions can facilitate tumor removal, improve patients\' quality of life, and prolong patients\' survival. In this case report, a 27-year-old young woman was diagnosed with MMNST of the cervical spinal cord due to weakness of her limbs in our hospital, and underwent surgical resection. The patient\'s limbs returned to normal after surgery. It is worth mentioning that the patient visited our hospital 7 months ago for \"right upper limb pain for 3 days\" and was diagnosed with a cervical spine space-occupying lesion at the same position this time, but the pathology report was \"hemosiderosis\". The patient\'s limbs returned to normal after surgery. It is worth mentioning that the patient visited our hospital 7 months ago for \"right upper limb pain for 3 days\" and was diagnosed with a cervical spine space-occupying lesion at the same position this time, but the pathology report was \"hemosiderosis\". This case report aims to raise awareness of the problem of spinal cord MMNST and contribute to greater knowledge of this rare tumor. This case report aims to raise awareness of the problem of spinal cord MMNST and contribute to greater knowledge of this rare tumor.
摘要:
脊髓恶性黑色素神经鞘瘤(MMNST)是一种罕见的中枢神经体系肿瘤,起源于脊髓或脊髓髓鞘细胞,可产生黑色素。这种类型的肿瘤通常是高度侵袭性和恶性的,预后不良。脊髓MMNST的临床表现主要为疼痛,感觉异常,肌肉无力,肌肉萎缩,等。,脊髓压迫的症状,如肠和膀胱功能障碍,截瘫,等。早期发现肿瘤病灶可以促进肿瘤切除,提高患者的生活质量,延长患者的生存期.在这个案例报告中,一名27岁的年轻女子在我们医院因四肢无力被诊断为颈脊髓MMNST,接受了手术切除.手术后病人的四肢恢复正常。值得一提的是,该患者于7个月前因“右上肢疼痛3天”来我院就诊,这次被诊断为同一位置的颈椎占位性病变,但病理报告是“含铁血黄素沉着症”。手术后病人的四肢恢复正常。值得一提的是,该患者于7个月前因“右上肢疼痛3天”来我院就诊,这次被诊断为同一位置的颈椎占位性病变,但病理报告是“含铁血黄素沉着症”。此病例报告旨在提高对脊髓MMNST问题的认识,并有助于对这种罕见肿瘤的更多了解。此病例报告旨在提高对脊髓MMNST问题的认识,并有助于对这种罕见肿瘤的更多了解。
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