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Abstract：
BACKGROUND: This study aimed to investigate the knowledge, attitudes, and practices (KAP) toward cardiovascular complications among end-stage renal disease patients undergoing maintenance hemodialysis.
METHODS: This web-based cross-sectional study was conducted at Guangdong Provincial People\'s Hospital between December 2022, and May 2023.
RESULTS: A total of 545 valid questionnaires were collected, with an average age of 57.72 ± 13.47 years. The mean knowledge, attitudes and practices scores were 8.17 ± 2.9 (possible range: 0-24), 37.63 ± 3.80 (possible range: 10-50), 33.07 ± 6.10 (possible range: 10-50) respectively. Multivariate logistic regression analysis showed that patients from non-urban area had lower knowledge compared to those from urban area (odds ratio (OR) = 0.411, 95% CI: 0.262-0.644, P < 0.001). Furthermore, higher levels of education were associated with better knowledge, as indicated by OR for college and above (OR = 4.858, 95% CI: 2.483-9.504), high school/vocational school (OR = 3.457, 95% CI: 1.930-6.192), junior high school (OR = 3.300, 95% CI: 1.945-5.598), with primary school and below as reference group (all P < 0.001). Besides, better knowledge (OR = 1.220, 95% CI: 1.132-1.316, P < 0.001) and higher educational levels were independently associated with positive attitudes. Specifically, individuals with a college degree and above (OR = 2.986, 95% CI: 1.411-6.321, P = 0.004) and those with high school/vocational school education (OR = 2.418, 95% CI: 1.314-4.451, P = 0.005) have more positive attitude, with primary school and below as reference group. Next, better attitude (OR = 1.174, 95% CI: 1.107-1.246, P < 0.001) and higher education were independently associated with proactive practices. Those with college and above (OR = 2.870, 95% CI: 1.359-6.059, P = 0.006), and those with high school/vocational school education (OR = 1.886, 95% CI: 1.032-3.447, P = 0.039) had more proactive practices, with primary school and below as reference group.
CONCLUSIONS: End-stage renal disease patients undergoing maintenance hemodialysis demonstrated insufficient knowledge, positive attitudes, and moderate practices regarding cardiovascular complications. Targeted interventions should prioritize improving knowledge and attitudes, particularly among patients with lower educational levels and income, to enhance the management of cardiovascular complications in end-stage renal disease.
METHODS: This web-based cross-sectional study was conducted at Guangdong Provincial People\'s Hospital between December 2022, and May 2023.
RESULTS: A total of 545 valid questionnaires were collected, with an average age of 57.72 ± 13.47 years. The mean knowledge, attitudes and practices scores were 8.17 ± 2.9 (possible range: 0-24), 37.63 ± 3.80 (possible range: 10-50), 33.07 ± 6.10 (possible range: 10-50) respectively. Multivariate logistic regression analysis showed that patients from non-urban area had lower knowledge compared to those from urban area (odds ratio (OR) = 0.411, 95% CI: 0.262-0.644, P < 0.001). Furthermore, higher levels of education were associated with better knowledge, as indicated by OR for college and above (OR = 4.858, 95% CI: 2.483-9.504), high school/vocational school (OR = 3.457, 95% CI: 1.930-6.192), junior high school (OR = 3.300, 95% CI: 1.945-5.598), with primary school and below as reference group (all P < 0.001). Besides, better knowledge (OR = 1.220, 95% CI: 1.132-1.316, P < 0.001) and higher educational levels were independently associated with positive attitudes. Specifically, individuals with a college degree and above (OR = 2.986, 95% CI: 1.411-6.321, P = 0.004) and those with high school/vocational school education (OR = 2.418, 95% CI: 1.314-4.451, P = 0.005) have more positive attitude, with primary school and below as reference group. Next, better attitude (OR = 1.174, 95% CI: 1.107-1.246, P < 0.001) and higher education were independently associated with proactive practices. Those with college and above (OR = 2.870, 95% CI: 1.359-6.059, P = 0.006), and those with high school/vocational school education (OR = 1.886, 95% CI: 1.032-3.447, P = 0.039) had more proactive practices, with primary school and below as reference group.
CONCLUSIONS: End-stage renal disease patients undergoing maintenance hemodialysis demonstrated insufficient knowledge, positive attitudes, and moderate practices regarding cardiovascular complications. Targeted interventions should prioritize improving knowledge and attitudes, particularly among patients with lower educational levels and income, to enhance the management of cardiovascular complications in end-stage renal disease.
摘要：
背景：本研究旨在调查知识，态度，在接受维持性血液透析的终末期肾病患者中，心血管并发症和实践（KAP）。
方法：这项基于网络的横断面研究于2022年12月至2023年5月在广东省人民医院进行。
结果：共收集有效问卷545份，平均年龄57.72±13.47岁。卑鄙的知识，态度和实践得分为8.17±2.9（可能范围：0-24），37.63±3.80（可能范围：10-50），分别为33.07±6.10(可能范围:10-50)。多因素logistic回归分析显示，非城市地区患者的知识水平低于城市地区（比值比（OR）=0.411，95％CI：0.262-0.644，P<0.001）。此外，更高的教育水平与更好的知识有关，如大学及以上的OR所示(OR=4.858，95%CI：2.483-9.504)，高中/职业学校(OR=3.457，95%CI：1.930-6.192)，初中（OR=3.300，95%CI：1.945-5.598），以小学及以下为参照组(均P<0.001)。此外,较高的知识水平（OR=1.220，95％CI：1.132-1.316，P<0.001）和较高的教育水平与积极态度独立相关。具体来说,具有大专及以上学历(OR=2.986,95%CI:1.411-6.321,P=0.004)和具有高中/职业学校教育(OR=2.418,95%CI:1.314-4.451,P=0.005)的人态度更加积极,以小学及以下为参照组。接下来,良好的态度（OR=1.174，95％CI：1.107-1.246，P<0.001）和高等教育与主动实践独立相关。大专及以上学历（OR=2.870，95%CI：1.359-6.059，P=0.006），和那些高中/职业学校教育（OR=1.886，95％CI：1.032-3.447，P=0.039）有更积极的做法，以小学及以下为参照组。
结论：接受维持性血液透析的终末期肾病患者知识不足，积极的态度，和关于心血管并发症的适度做法。有针对性的干预措施应优先改善知识和态度，特别是在教育水平和收入较低的患者中，加强终末期肾病心血管并发症的管理。
方法：这项基于网络的横断面研究于2022年12月至2023年5月在广东省人民医院进行。
结果：共收集有效问卷545份，平均年龄57.72±13.47岁。卑鄙的知识，态度和实践得分为8.17±2.9（可能范围：0-24），37.63±3.80（可能范围：10-50），分别为33.07±6.10(可能范围:10-50)。多因素logistic回归分析显示，非城市地区患者的知识水平低于城市地区（比值比（OR）=0.411，95％CI：0.262-0.644，P<0.001）。此外，更高的教育水平与更好的知识有关，如大学及以上的OR所示(OR=4.858，95%CI：2.483-9.504)，高中/职业学校(OR=3.457，95%CI：1.930-6.192)，初中（OR=3.300，95%CI：1.945-5.598），以小学及以下为参照组(均P<0.001)。此外,较高的知识水平（OR=1.220，95％CI：1.132-1.316，P<0.001）和较高的教育水平与积极态度独立相关。具体来说,具有大专及以上学历(OR=2.986,95%CI:1.411-6.321,P=0.004)和具有高中/职业学校教育(OR=2.418,95%CI:1.314-4.451,P=0.005)的人态度更加积极,以小学及以下为参照组。接下来,良好的态度（OR=1.174，95％CI：1.107-1.246，P<0.001）和高等教育与主动实践独立相关。大专及以上学历（OR=2.870，95%CI：1.359-6.059，P=0.006），和那些高中/职业学校教育（OR=1.886，95％CI：1.032-3.447，P=0.039）有更积极的做法，以小学及以下为参照组。
结论：接受维持性血液透析的终末期肾病患者知识不足，积极的态度，和关于心血管并发症的适度做法。有针对性的干预措施应优先改善知识和态度，特别是在教育水平和收入较低的患者中，加强终末期肾病心血管并发症的管理。
