关键词: Case report Head and neck infection Internal jugular vein thrombosis Lemierre’s syndrome Surgical treatment

Mesh : Humans Lemierre Syndrome / surgery diagnosis drug therapy Male Jugular Veins / surgery Aged Treatment Outcome Ligation Anti-Bacterial Agents / therapeutic use Drainage Tomography, X-Ray Computed Venous Thrombosis / surgery

来  源:   DOI:10.1186/s13256-024-04584-2   PDF(Pubmed)

Abstract:
BACKGROUND: Lemierre\'s syndrome is a fatal and rare disease that is typically characterized by oropharyngeal infection and internal jugular vein thrombosis. Timely institution of appropriate antibiotics is the standard treatment.
METHODS: The authors report a case of Lemierre\'s syndrome. A 67-year-old male patient of Han ethnicity in China suffered from a large inflammatory neck mass involving left internal jugular vein thrombosis diagnosed as Lemierre\'s syndrome and finally cured by surgical treatment. In addition, a literature review was carried out through PubMed using the terms \"Lemierre\'s syndrome/disease and review, meta-analysis or retrospective study\" and \"Lemierre\'s syndrome/disease and internal jugular vein\". This search yielded six articles that recorded surgical methods such as drainage, craniotomy, tooth extraction, and ligation of the occluded vein to give clinicians more ideas about the treatment of the Lemierre\'s syndrome.
CONCLUSIONS: This is the first review to summarize the conditions under which surgical treatment are conducted. Additionally, this is the first report of such a large inflammatory neck mass that was completely cured by surgical resection and internal jugular vein ligation. The authors also offer several conclusions regarding surgical intervention in Lemierre\'s syndrome for the first time.
摘要:
背景:Lemierre综合征是一种致命且罕见的疾病,通常以口咽部感染和颈内静脉血栓形成为特征。及时使用适当的抗生素是标准治疗方法。
方法:作者报告一例Lemierre综合征。一名67岁的中国汉族男性患者患有巨大的炎性颈部肿块,涉及左颈内静脉血栓形成,诊断为Lemierre综合征,最终通过手术治疗治愈。此外,通过PubMed进行了文献综述,使用术语“Lemierre综合征/疾病和综述,荟萃分析或回顾性研究“和”Lemierre综合征/疾病和颈内静脉“。这次搜索产生了六篇记录手术方法的文章,例如引流,开颅手术,拔牙,和闭塞静脉的结扎,为临床医生提供更多关于Lemierre综合征治疗的想法。
结论:这是第一个总结手术治疗条件的综述。此外,这是首次报道如此大的炎性颈部肿块,通过手术切除和颈内静脉结扎术完全治愈。作者还首次就Lemierre综合征的手术干预提供了一些结论。
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