PDF(Pubmed)
Abstract：
BACKGROUND: Depression is a symptom characterized by sadness, loss of interest or pleasure, feelings of guilt or low self-worth, disturbed sleep or appetite, feelings of tiredness and poor concentration. One of the most common mental illnesses in the world and a major contributor to morbidity and mortality is depression. The purpose of this study was to ascertain the prevalence of depression and the risk factors associated with it in women who had advanced pelvic organ prolapse.
METHODS: A facility-based cross-sectional study was conducted to determine depression among advanced pelvic organ prolapse women at Gondar University Comprehensive Specialized Hospital. All women who have advanced pelvic organ prolapse were consecutively included till it reached a total of 367 participants over four months. A structured questionnaire was used to obtain the sociodemographic characteristics, clinical characteristics and depression status of the participants. Depression measures were obtained by using the Patient Health Questionnaire tool, which is validated in the Ethiopian local language for chronic illnesses including pelvic organ prolapse using a cut point of five and above, which is considered to indicate depression. Women who screened positive were linked to a psychiatric clinic for further evaluation and treatment. Data was entered into a computer using Epi Info version 3.5.3 and then exported to STATA version 14 for analysis. Multivariable logistic regressions were fitted and odds ratios with 95% confidence intervals with a P value less than 0.05 were used to identify statistically significant factors.
RESULTS: The prevalence of depression was found to be 47.1% (95% CI: 43-52%). Being rural (AOR = 4.8; CI: 1.11-16.32), having a history of divorce because of pelvic organ prolapse (AOR = 5.5; CI: 1.85-16.32) and having a history of urinary symptoms (AOR = 3.1; CI: 1.12-8.59) were found to be independently associated with depression.
CONCLUSIONS: The prevalence of depression among women with advanced pelvic organ prolapse in this study is high as compared to other studies. Depression screening strategies should be designed for the early identification and treatment of depression among women with advanced pelvic organ prolapse.
METHODS: A facility-based cross-sectional study was conducted to determine depression among advanced pelvic organ prolapse women at Gondar University Comprehensive Specialized Hospital. All women who have advanced pelvic organ prolapse were consecutively included till it reached a total of 367 participants over four months. A structured questionnaire was used to obtain the sociodemographic characteristics, clinical characteristics and depression status of the participants. Depression measures were obtained by using the Patient Health Questionnaire tool, which is validated in the Ethiopian local language for chronic illnesses including pelvic organ prolapse using a cut point of five and above, which is considered to indicate depression. Women who screened positive were linked to a psychiatric clinic for further evaluation and treatment. Data was entered into a computer using Epi Info version 3.5.3 and then exported to STATA version 14 for analysis. Multivariable logistic regressions were fitted and odds ratios with 95% confidence intervals with a P value less than 0.05 were used to identify statistically significant factors.
RESULTS: The prevalence of depression was found to be 47.1% (95% CI: 43-52%). Being rural (AOR = 4.8; CI: 1.11-16.32), having a history of divorce because of pelvic organ prolapse (AOR = 5.5; CI: 1.85-16.32) and having a history of urinary symptoms (AOR = 3.1; CI: 1.12-8.59) were found to be independently associated with depression.
CONCLUSIONS: The prevalence of depression among women with advanced pelvic organ prolapse in this study is high as compared to other studies. Depression screening strategies should be designed for the early identification and treatment of depression among women with advanced pelvic organ prolapse.
摘要：
背景：抑郁症是一种以悲伤为特征的症状，失去兴趣或快乐，内疚或低自我价值感，睡眠或食欲受到干扰，疲倦和注意力不集中的感觉。抑郁症是世界上最常见的精神疾病之一，也是发病率和死亡率的主要原因。这项研究的目的是确定患有晚期盆腔器官脱垂的女性中抑郁症的患病率及其相关危险因素。
方法：在冈达尔大学综合专科医院进行了一项基于设施的横断面研究，以确定晚期盆腔器官脱垂妇女的抑郁症。所有患有晚期盆腔器官脱垂的女性都被连续纳入，直到在四个月内达到367名参与者。使用结构化问卷获得社会人口统计学特征，参与者的临床特征和抑郁状态。抑郁测量是通过使用患者健康问卷工具获得的，这在埃塞俄比亚当地语言中被证实用于慢性疾病，包括盆腔器官脱垂，使用5个以上的切点，这被认为表明抑郁。筛查阳性的妇女与精神病诊所联系，以进行进一步的评估和治疗。使用EpiInfo版本3.5.3将数据输入计算机，然后导出到STATA版本14进行分析。拟合多变量逻辑回归，并使用P值小于0.05的95％置信区间的比值比来识别具有统计学意义的因素。
结果：发现抑郁症的患病率为47.1％（95％CI：43-52％）。农村（AOR=4.8；CI：1.11-16.32），有盆腔器官脱垂离婚史(AOR=5.5;CI:1.85-16.32)和有泌尿系症状史(AOR=3.1;CI:1.12-8.59)与抑郁症独立相关.
结论：与其他研究相比，本研究中晚期盆腔器官脱垂女性的抑郁症患病率较高。应设计抑郁症筛查策略，以早期识别和治疗晚期盆腔器官脱垂女性的抑郁症。
方法：在冈达尔大学综合专科医院进行了一项基于设施的横断面研究，以确定晚期盆腔器官脱垂妇女的抑郁症。所有患有晚期盆腔器官脱垂的女性都被连续纳入，直到在四个月内达到367名参与者。使用结构化问卷获得社会人口统计学特征，参与者的临床特征和抑郁状态。抑郁测量是通过使用患者健康问卷工具获得的，这在埃塞俄比亚当地语言中被证实用于慢性疾病，包括盆腔器官脱垂，使用5个以上的切点，这被认为表明抑郁。筛查阳性的妇女与精神病诊所联系，以进行进一步的评估和治疗。使用EpiInfo版本3.5.3将数据输入计算机，然后导出到STATA版本14进行分析。拟合多变量逻辑回归，并使用P值小于0.05的95％置信区间的比值比来识别具有统计学意义的因素。
结果：发现抑郁症的患病率为47.1％（95％CI：43-52％）。农村（AOR=4.8；CI：1.11-16.32），有盆腔器官脱垂离婚史(AOR=5.5;CI:1.85-16.32)和有泌尿系症状史(AOR=3.1;CI:1.12-8.59)与抑郁症独立相关.
结论：与其他研究相比，本研究中晚期盆腔器官脱垂女性的抑郁症患病率较高。应设计抑郁症筛查策略，以早期识别和治疗晚期盆腔器官脱垂女性的抑郁症。
