Abstract：
Oral immunotherapy (OIT) is an alternative treatment of IgE-mediated food allergy that has been shown to increase tolerance threshold to many of the top food allergens, although this effect may be dependent on age, dose, frequency, and duration. OIT has been shown to be effective and safe in infants, and early initiation can improve rates of desensitization even for those foods whose natural history favors loss of allergy. Studies looking at protocol modification to improve OIT success are ongoing as is the evaluation of clinical tools to help monitor OIT effects.
摘要：
口服免疫疗法（OIT）是IgE介导的食物过敏的一种替代疗法，已被证明可以增加对许多顶级食物过敏原的耐受阈值。虽然这种影响可能取决于年龄，剂量,频率,和持续时间。OIT已被证明对婴儿是有效和安全的，即使对于那些自然史倾向于失去过敏的食物，早期开始也可以提高脱敏率。正在进行研究方案修改以改善OIT成功的研究，以及评估临床工具以帮助监测OIT效果的研究。
