hnRNPM 通过抑制 LINE 相关的隐蔽剪接来防止 dsRNA 介导的干扰素应答。
关键词: ALU LINE RNA-binding protein cancer cryptic splicing double-stranded RNA hnRNPM interferon response
Mesh : Humans Heterogeneous-Nuclear Ribonucleoprotein Group M / genetics metabolism RNA, Double-Stranded / genetics metabolism Introns RNA Splicing Long Interspersed Nucleotide Elements / genetics Interferons / metabolism genetics Animals HEK293 Cells Mice Transcriptome Exons RNA Splice Sites Alu Elements / genetics
来 源:
DOI:10.1016/j.molcel.2024.05.004
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