Abstract：
Previous studies have reported that polyhexamethylene biguanide (PHMB) and betaine solution and gels remove biofilm, improve wound healing and reduce infection rates. Quality of life (QoL) outcomes are not commonly reported on when it comes to wound care. This review aims to summarise QoL data from a cohort of case studies previously published on chronic lower limb ulcers using PHMB products (Prontosan® Solution, Prontosan® Wound Gel X and Prontosan® Debridement Pad). Here, we report on and review a total of 38 case studies describing 56 wounds. From these 38 case studies, 36 reported that all the wounds involved had either healed or improved by the end of their respective study period. QoL themes explore malodour, slough, and exudate, pain, mobility, hair growth, antibiotic intake, return to work, social life and mood. This case series demonstrates that treatment with Prontosan® products improves many QoL outcomes for patients with non-healing wounds.
摘要：
以前的研究报道，聚六亚甲基双胍（PHMB）和甜菜碱溶液和凝胶去除生物膜，改善伤口愈合，降低感染率。当涉及到伤口护理时,通常不报告生活质量(QoL)结果。这篇综述旨在总结以前发表的关于使用PHMB产品的慢性下肢溃疡的一组案例研究的QoL数据（Prontosan®解决方案，Prontosan®伤口凝胶X和Prontosan®清创垫)。这里,我们共报告并回顾了38项案例研究，描述了56处伤口。从这38个案例研究中，36报告说，到各自的研究期结束时，所有涉及的伤口都已愈合或改善。QoL主题探索恶臭，泥泞，和渗出物，疼痛,移动性,头发生长,抗生素摄入量，重返工作岗位,社交生活和情绪。本病例系列表明，使用Prontosan®产品治疗可改善伤口未愈合患者的许多QoL结果。
