高糖通过激活 mTOR 增强人纤维环细胞纤维化,PKC δ,和 NF - κ B 信号通路。
关键词: IVDD NF-κB fibrosis high glucose
Mesh : Humans TOR Serine-Threonine Kinases / metabolism Signal Transduction Protein Kinase C-delta / metabolism Fibrosis / metabolism NF-kappa B / metabolism Glucose / metabolism Annulus Fibrosus / metabolism pathology Intervertebral Disc Degeneration / metabolism pathology Male Female Middle Aged Cells, Cultured Adult
来 源:
DOI:10.18632/aging.205876
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