PDF(Pubmed)
Abstract：
UNASSIGNED: Craniocervical junction (CCJ) can be involved in inflammatory arthritis. We aimed to define types of CCJ involvement in rheumatoid arthritis (RA), spondyloarthritis (SpA), and psoriatic arthritis (PsA) and compare them with patients without inflammatory arthritides.
UNASSIGNED: In this retrospective analysis, cervical CT or MRIs of patients with RA, SpA, or PsA, taken for any reason between 2010 and 2020, according to ICD-10 codes, were scanned. Demographic data of the patients were recorded. CCJ involvements (atlantoaxial, vertical, or subaxial subluxation, odontoid process involvement) were reevaluated by an experienced radiologist. The control group consisted of consecutive patients without inflammatory arthritis.
UNASSIGNED: Exactly 459 patients (204 RA, 200 SpA, and 55 PsA) and 78 patients in the control group were included in the study. CCJ involvement was detected in 101 (49.5%) RA, 53 (26.5%) SpA, 10 (18.2%) PsA, and 4 patients (5.1%) in the control group (p < 0.001). The odontoid process was one of the main targets, especially in RA patients (69 (33.8%)), which was significantly higher than in the SpA, PsA, and control groups. Although vertical subluxation (VS) was numerically higher in the RA and SpA groups compared to the control group, VS-related brainstem compression was relatively uncommon: 6 (2.9%) in RA, 1 (0.5%) in AS, and none in the PsA and control groups.
UNASSIGNED: CCJ involvement can often be detected in patients with inflammatory arthritis, especially in RA and SpA patients. The odontoid process is the main target of inflammation.
UNASSIGNED: In this retrospective analysis, cervical CT or MRIs of patients with RA, SpA, or PsA, taken for any reason between 2010 and 2020, according to ICD-10 codes, were scanned. Demographic data of the patients were recorded. CCJ involvements (atlantoaxial, vertical, or subaxial subluxation, odontoid process involvement) were reevaluated by an experienced radiologist. The control group consisted of consecutive patients without inflammatory arthritis.
UNASSIGNED: Exactly 459 patients (204 RA, 200 SpA, and 55 PsA) and 78 patients in the control group were included in the study. CCJ involvement was detected in 101 (49.5%) RA, 53 (26.5%) SpA, 10 (18.2%) PsA, and 4 patients (5.1%) in the control group (p < 0.001). The odontoid process was one of the main targets, especially in RA patients (69 (33.8%)), which was significantly higher than in the SpA, PsA, and control groups. Although vertical subluxation (VS) was numerically higher in the RA and SpA groups compared to the control group, VS-related brainstem compression was relatively uncommon: 6 (2.9%) in RA, 1 (0.5%) in AS, and none in the PsA and control groups.
UNASSIGNED: CCJ involvement can often be detected in patients with inflammatory arthritis, especially in RA and SpA patients. The odontoid process is the main target of inflammation.
摘要：
■颅颈交界处（CCJ）可能与炎性关节炎有关。我们旨在定义类风湿关节炎（RA）中CCJ的类型，脊柱关节炎(SpA),和银屑病关节炎（PsA），并将其与无炎性关节炎的患者进行比较。
■在此回顾性分析中，RA患者的宫颈CT或MRI，SpA,或PsA，根据ICD-10代码，在2010年至2020年期间，被扫描。记录患者的人口统计学数据。CCJ卷入（寰枢椎，垂直,或轴下脱位，齿状突受累）由经验丰富的放射科医生重新评估。对照组由无炎性关节炎的连续患者组成。
■恰好459例患者（204例RA，200SpA,55PsA）和对照组78例患者被纳入研究。在101例（49.5%）RA中检测到CCJ参与，53（26.5%）SpA，10（18.2%）PSA，对照组4例(5.1%)(p<0.001)。齿状突进程是其主要目标之一,尤其是RA患者（69（33.8％）），明显高于SpA，PsA,和对照组。尽管与对照组相比，RA和SpA组的垂直半脱位（VS）在数值上较高，与VS相关的脑干压迫相对不常见：RA中6例（2.9％），1（0.5%）在AS中，PsA和对照组均无。
■通常可以在炎症性关节炎患者中检测到CCJ受累，尤其是RA和SpA患者。齿状突进程是炎症的主要目标。
■在此回顾性分析中，RA患者的宫颈CT或MRI，SpA,或PsA，根据ICD-10代码，在2010年至2020年期间，被扫描。记录患者的人口统计学数据。CCJ卷入（寰枢椎，垂直,或轴下脱位，齿状突受累）由经验丰富的放射科医生重新评估。对照组由无炎性关节炎的连续患者组成。
■恰好459例患者（204例RA，200SpA,55PsA）和对照组78例患者被纳入研究。在101例（49.5%）RA中检测到CCJ参与，53（26.5%）SpA，10（18.2%）PSA，对照组4例(5.1%)(p<0.001)。齿状突进程是其主要目标之一,尤其是RA患者（69（33.8％）），明显高于SpA，PsA,和对照组。尽管与对照组相比，RA和SpA组的垂直半脱位（VS）在数值上较高，与VS相关的脑干压迫相对不常见：RA中6例（2.9％），1（0.5%）在AS中，PsA和对照组均无。
■通常可以在炎症性关节炎患者中检测到CCJ受累，尤其是RA和SpA患者。齿状突进程是炎症的主要目标。
