PDF(Pubmed)
Abstract：
This case report demonstrates the management of primary infertility in a couple: the male was 37 years old and the female was 32 years old. The female had a submucosal uterine fibroid. Later, the female underwent a myomectomy to remove submucosal fibroids in the uterus after two failed intrauterine insemination (IUI) cycles. After six months of her recovery period, she underwent ovum pickup for an in vitro fertilization (IVF) cycle. During the process of ovum pickup (OPU), four oocytes were retrieved: three in the metaphase one (M1) stage and one in the metaphase two (M2) stage. Subsequently, the couple underwent in vitro maturation (IVM) of oocytes, where the M1 stage oocytes were cultured for six hours. The M1 stage oocytes progressed to the M2 stage. These oocytes were then injected with sperm, which resulted in the formation of two blastocysts. These blastocysts were then cryopreserved for three months, and after three months, these frozen embryos were then transferred, leading to the successful conception. The case study evaluates a couple who suffered from infertility. This study includes a treatment of myomectomy and in vitro maturation.
摘要：
该病例报告显示了一对夫妇原发性不孕症的治疗方法：男性37岁，女性32岁。女性患有粘膜下子宫肌瘤。稍后，在两个宫腔内人工授精(IUI)周期失败后,该女性行子宫肌瘤切除术,以切除子宫粘膜下肌瘤.经过六个月的恢复期，她接受了体外受精（IVF）周期的卵子拾取。在卵子拾取(OPU)的过程中，回收了四个卵母细胞：三个在中期一（M1）阶段，一个在中期二（M2）阶段。随后，这对夫妇经历了卵母细胞的体外成熟（IVM），其中M1期卵母细胞培养6小时。M1期卵母细胞进展到M2期。然后给这些卵母细胞注射精子，这导致了两个胚泡的形成。然后将这些胚泡冷冻保存三个月，三个月后,然后转移这些冷冻胚胎，导致成功的概念。该案例研究评估了一对患有不孕症的夫妇。这项研究包括子宫肌瘤切除术和体外成熟的治疗。
