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Abstract：
UNASSIGNED: Colpocleisis is one of traditional surgical procedures for elderly and frail women with advanced pelvic organ prolapse. The occurrence of de novo urinary incontinence following colpocleisis was considered to impair the postoperative quality of life. The incidence of de novo urinary incontinence after colpocleisis has been reported to be ranging from 6.6 % to 27 %. There was an absence of prospective large-sample study to investigate the accurate incidence of de novo urinary incontinence following colpocleisis and the impact on the quality of life till now.
UNASSIGNED: s The primary objective was to report the incidence of de novo urinary incontinence after colpocleisis. The second objectives were to evaluate the long-term quality of life in patients with de novo urinary incontinence, and to conduct detailed pre- and post-operative evaluations of lower urinary tract symptoms.
UNASSIGNED: This prospective study included 253 patients with symptomatic pelvic organ prolapse who underwent colpocleisis between 2009 and 2021. De novo urinary incontinence was defined as the occurrence of urinary incontinence 3 months postoperatively. All patients were required to complete the Urinary Distress Inventory questionnaire and the Urinary Impact Questionnaire for the evaluation of patients\' quality of life, and the Patient Global Impression of Improvement questionnaire for the evaluation of patients\' satisfaction.
UNASSIGNED: 245 patients (245/253, 96·8 %) completed the 3-month follow-up, and were included in the final analysis. The incidence of de novo urinary incontinence was 5.4 % (10/185). There was no significant difference in the Urinary Distress Inventory -6 scores (22.50 vs. 10.30, P = 0.276) or the subjective satisfaction rate (100 % vs. 98.9 %, P = 0.250) between the patients with or without de novo urinary incontinence at the long-term follow-up. The incidence of voiding difficulty was significantly reduced after colpocleisis (27.8 % vs. 0.0 %, P < 0.001). The patients\' quality of life indicated by Urinary Distress Inventory-6 and Urinary Impact Questionnaire-7 scores were significantly improved postoperatively (26.27 vs. 13.39, and 19.13 vs. 6.05, P < 0.05).
UNASSIGNED: The incidence of de novo urinary incontinence after colpocleisis was very low. Patients\' quality of life, and low urinary tract symptoms were significantly improved after colpocleisis.
UNASSIGNED: s The primary objective was to report the incidence of de novo urinary incontinence after colpocleisis. The second objectives were to evaluate the long-term quality of life in patients with de novo urinary incontinence, and to conduct detailed pre- and post-operative evaluations of lower urinary tract symptoms.
UNASSIGNED: This prospective study included 253 patients with symptomatic pelvic organ prolapse who underwent colpocleisis between 2009 and 2021. De novo urinary incontinence was defined as the occurrence of urinary incontinence 3 months postoperatively. All patients were required to complete the Urinary Distress Inventory questionnaire and the Urinary Impact Questionnaire for the evaluation of patients\' quality of life, and the Patient Global Impression of Improvement questionnaire for the evaluation of patients\' satisfaction.
UNASSIGNED: 245 patients (245/253, 96·8 %) completed the 3-month follow-up, and were included in the final analysis. The incidence of de novo urinary incontinence was 5.4 % (10/185). There was no significant difference in the Urinary Distress Inventory -6 scores (22.50 vs. 10.30, P = 0.276) or the subjective satisfaction rate (100 % vs. 98.9 %, P = 0.250) between the patients with or without de novo urinary incontinence at the long-term follow-up. The incidence of voiding difficulty was significantly reduced after colpocleisis (27.8 % vs. 0.0 %, P < 0.001). The patients\' quality of life indicated by Urinary Distress Inventory-6 and Urinary Impact Questionnaire-7 scores were significantly improved postoperatively (26.27 vs. 13.39, and 19.13 vs. 6.05, P < 0.05).
UNASSIGNED: The incidence of de novo urinary incontinence after colpocleisis was very low. Patients\' quality of life, and low urinary tract symptoms were significantly improved after colpocleisis.
摘要：
■Colpocleisis是老年和体弱女性晚期盆腔器官脱垂的传统外科手术之一。阴道闭锁术后新发尿失禁的发生被认为会损害术后生活质量。据报道，阴道炎后新发尿失禁的发生率为6.6％至27％。到目前为止，尚无前瞻性大样本研究来调查阴道闭锁术后新发尿失禁的准确发生率以及对生活质量的影响。
■的主要目的是报告阴道炎后从头尿失禁的发生率。第二个目标是评估从头尿失禁患者的长期生活质量，并对下尿路症状进行详细的术前和术后评估。
■这项前瞻性研究纳入了253例有症状的盆腔器官脱垂患者，这些患者在2009年至2021年之间接受了阴道切除术。新发尿失禁定义为术后3个月发生尿失禁。所有患者均需填写《尿路困扰量表》和《尿路影响问卷》，以评估患者的生活质量。以及用于评估患者满意度的患者总体改善印象问卷。
■245例患者（245/253，96·8%）完成了3个月的随访，并纳入最终分析。从头尿失禁的发生率为5.4％（10/185）。尿路窘迫量表-6得分没有显着差异（22.50vs.10.30，P=0.276）或主观满意率（100%vs.98.9%,在长期随访中，有或没有新发尿失禁的患者之间的P=0.250）。阴道炎后排尿困难的发生率显着降低（27.8%vs.0.0%,P<0.001)。尿路窘迫量表-6和尿路影响问卷-7评分显示的患者生活质量在术后显著改善(26.27vs.13.39和19.13vs.6.05,P<0.05)。
■阴道炎术后从头尿失禁的发生率很低。患者的生活质量，阴道镜术后下尿路症状明显改善。
■的主要目的是报告阴道炎后从头尿失禁的发生率。第二个目标是评估从头尿失禁患者的长期生活质量，并对下尿路症状进行详细的术前和术后评估。
■这项前瞻性研究纳入了253例有症状的盆腔器官脱垂患者，这些患者在2009年至2021年之间接受了阴道切除术。新发尿失禁定义为术后3个月发生尿失禁。所有患者均需填写《尿路困扰量表》和《尿路影响问卷》，以评估患者的生活质量。以及用于评估患者满意度的患者总体改善印象问卷。
■245例患者（245/253，96·8%）完成了3个月的随访，并纳入最终分析。从头尿失禁的发生率为5.4％（10/185）。尿路窘迫量表-6得分没有显着差异（22.50vs.10.30，P=0.276）或主观满意率（100%vs.98.9%,在长期随访中，有或没有新发尿失禁的患者之间的P=0.250）。阴道炎后排尿困难的发生率显着降低（27.8%vs.0.0%,P<0.001)。尿路窘迫量表-6和尿路影响问卷-7评分显示的患者生活质量在术后显著改善(26.27vs.13.39和19.13vs.6.05,P<0.05)。
■阴道炎术后从头尿失禁的发生率很低。患者的生活质量，阴道镜术后下尿路症状明显改善。
