METHODS: A prospective longitudinal study was conducted at a teaching tertiary care institute in Central India, involving COVID-19 patients from May 2020 to September 2021. Participants, aged 18 or older, diagnosed with COVID-19 and surviving until the last follow-up, were monitored telephonically and during outpatient visits for treatment details and outcomes. Data analysis was done using R software 4.2.1.
RESULTS: The baseline characteristics of the study participants showed a majority of moderate COVID-19 severity (47.5%), with a higher proportion of males (64.8%) affected. Common comorbidities included diabetes (27.1%) and hypertension (22.9%). Long COVID-19 symptoms, notably breathlessness, were prevalent, with females exhibiting a significantly higher association. Pulmonary function abnormalities were associated with both long COVID-19 symptoms and higher COVID-19 severity categories, indicating lasting respiratory impact post-infection.
CONCLUSIONS: Long after the pandemic, COVID-19 continues to raise concerns due to persistent sequelae, with a majority experiencing long COVID symptoms, particularly those with severe initial illness, including breathlessness and abnormal lung function, highlighting prevalent restrictive lung pattern changes.
方法:在印度中部的教学三级保健机构进行了一项前瞻性纵向研究,涉及2020年5月至2021年9月的COVID-19患者。参与者,18岁或以上,诊断为COVID-19并存活到最后一次随访,在电话和门诊就诊期间对治疗细节和结果进行监测.使用R软件4.2.1进行数据分析。
结果:研究参与者的基线特征显示大多数为中度COVID-19严重程度(47.5%),受影响的男性比例较高(64.8%)。常见的合并症包括糖尿病(27.1%)和高血压(22.9%)。长COVID-19症状,尤其是呼吸困难,普遍存在,女性表现出明显更高的关联性。肺功能异常与长期COVID-19症状和较高COVID-19严重程度类别相关,表明感染后持续的呼吸道影响。
结论:大流行后很久,由于持续的后遗症,COVID-19继续引起人们的关注,大多数人都有长期的COVID症状,特别是那些患有严重初始疾病的人,包括呼吸困难和肺功能异常,突出普遍的限制性肺部模式变化。