PDF(Pubmed)
Abstract：
UNASSIGNED: To determine whether the late-follicular-phase progesterone to retrieved oocytes (P/O) ratio during in vitro fertilization (IVF)/intracytoplasmic sperm injection (ICSI) impacts pregnancy outcomes.
UNASSIGNED: 12,874 cycles were retrospectively categorized into four groups according to the P/O ratio percentile, with divisions at the 25th, 50th and 75th percentiles.
UNASSIGNED: The clinical pregnancy and live birth rates of fresh cycle embryos in Group D were significantly lower than those in the other three groups (45.1% and 39.0%, 43.2% and 37.2%, 39.6% and 33.5%, 33.4% and 28.2% in Group A, B, C, D, respectively; both P < 0.008). Multivariate logistic regression analysis revealed a significant negative correlation between the P/O ratio and live birth, particularly when the P/O ratio was ≥0.22 (OR = 0.862, 95% CI [0.774-0.959], P = 0.006).
UNASSIGNED: The P/O ratio has certain predictive value for IVF/ICSI pregnancy outcomes and can be used for decision-making decision regarding fresh embryo transfer.
UNASSIGNED: 12,874 cycles were retrospectively categorized into four groups according to the P/O ratio percentile, with divisions at the 25th, 50th and 75th percentiles.
UNASSIGNED: The clinical pregnancy and live birth rates of fresh cycle embryos in Group D were significantly lower than those in the other three groups (45.1% and 39.0%, 43.2% and 37.2%, 39.6% and 33.5%, 33.4% and 28.2% in Group A, B, C, D, respectively; both P < 0.008). Multivariate logistic regression analysis revealed a significant negative correlation between the P/O ratio and live birth, particularly when the P/O ratio was ≥0.22 (OR = 0.862, 95% CI [0.774-0.959], P = 0.006).
UNASSIGNED: The P/O ratio has certain predictive value for IVF/ICSI pregnancy outcomes and can be used for decision-making decision regarding fresh embryo transfer.
摘要：
■确定体外受精（IVF）/卵胞浆内单精子注射（ICSI）过程中卵泡晚期孕酮与卵母细胞（P/O）的比率是否会影响妊娠结局。
■根据P/O比百分位数将12,874个周期回顾性地分为四组。25号有分裂，第50和第75百分位数。
■D组新鲜周期胚胎的临床妊娠率和活产率明显低于其他三组(45.1%和39.0%,43.2%和37.2%，39.6%和33.5%，A组33.4%和28.2%，B,C,D,分别；两者P<0.008)。多因素logistic回归分析显示P/O比与活产呈显著负相关,特别是当P/O比≥0.22时(OR=0.862，95%CI[0.774-0.959]，P=0.006)。
■P/O比对IVF/ICSI妊娠结局具有一定的预测价值，可用于有关新鲜胚胎移植的决策。
■根据P/O比百分位数将12,874个周期回顾性地分为四组。25号有分裂，第50和第75百分位数。
■D组新鲜周期胚胎的临床妊娠率和活产率明显低于其他三组(45.1%和39.0%,43.2%和37.2%，39.6%和33.5%，A组33.4%和28.2%，B,C,D,分别；两者P<0.008)。多因素logistic回归分析显示P/O比与活产呈显著负相关,特别是当P/O比≥0.22时(OR=0.862，95%CI[0.774-0.959]，P=0.006)。
■P/O比对IVF/ICSI妊娠结局具有一定的预测价值，可用于有关新鲜胚胎移植的决策。
