Abstract：
BACKGROUND: Delirium is a significant concern in end-of-life care. Continuous monitoring of agitation levels using objective methods may have advantages over existing measurement scales.
OBJECTIVE: To examine whether an objective measure of activity scores measured using a sheet-type non-wearable sensor (Nemuri SCAN [NSCAN]) was correlated with agitation levels measured using the modified Richmond Agitation-Sedation Scale (RASS) in terminally ill patients with cancer.
METHODS: We conducted a single-center, prospective, observational study in a palliative care unit using the NSCAN to measure activity scores and the RASS to assess agitation levels. RASS scores were prospectively measured by ward nurses blinded to the NSCAN variables. A database was created to pair the RASS scores and activity scores at night on the same day.
RESULTS: During the observation period, 1209 patients were hospitalized, and 3028 pairs of assessments of 971 patients were analyzed. The NSCAN activity scores significantly increased with increasing RASS scores (Jonckheere-Terpstra test, p < 0.001). The mean values of the activity scores for each RASS score were RASS -5, 28.9; RASS -4, 36.4; RASS -3, 41.7; RASS -2, 57.4; RASS -1, 58.8; RASS 0, 62.6; RASS 1, 79.6; RASS 2, 106.5; and RASS 3, 118.7.
CONCLUSIONS: The NSCAN activity significantly correlated with modified RASS agitation scores. Real-time NSCAN data on agitation may aid timely interventions for optimal symptom control. To improve outcomes for patients suffering from terminal delirium, more research on monitoring tools is warranted.
OBJECTIVE: To examine whether an objective measure of activity scores measured using a sheet-type non-wearable sensor (Nemuri SCAN [NSCAN]) was correlated with agitation levels measured using the modified Richmond Agitation-Sedation Scale (RASS) in terminally ill patients with cancer.
METHODS: We conducted a single-center, prospective, observational study in a palliative care unit using the NSCAN to measure activity scores and the RASS to assess agitation levels. RASS scores were prospectively measured by ward nurses blinded to the NSCAN variables. A database was created to pair the RASS scores and activity scores at night on the same day.
RESULTS: During the observation period, 1209 patients were hospitalized, and 3028 pairs of assessments of 971 patients were analyzed. The NSCAN activity scores significantly increased with increasing RASS scores (Jonckheere-Terpstra test, p < 0.001). The mean values of the activity scores for each RASS score were RASS -5, 28.9; RASS -4, 36.4; RASS -3, 41.7; RASS -2, 57.4; RASS -1, 58.8; RASS 0, 62.6; RASS 1, 79.6; RASS 2, 106.5; and RASS 3, 118.7.
CONCLUSIONS: The NSCAN activity significantly correlated with modified RASS agitation scores. Real-time NSCAN data on agitation may aid timely interventions for optimal symptom control. To improve outcomes for patients suffering from terminal delirium, more research on monitoring tools is warranted.
摘要：
背景：谵妄是临终关怀中的一个重要问题。使用客观方法连续监测搅拌水平可能比现有的测量尺度具有优势。
目的：研究使用非穿戴式传感器（NemuriSCAN[NSCAN]）测量的活动评分的客观测量是否与使用改良的里士满激动镇静量表（RASS）测量的激动水平相关。
方法：我们进行了单中心，prospective,在姑息治疗病房进行观察性研究，使用NSCAN测量活动评分，使用RASS评估躁动水平。RASS评分是由对NSCAN变量不知情的病房护士前瞻性测量的。创建了一个数据库，以在同一天晚上将RASS分数和活动分数配对。
结果：在观察期间，1209例患者住院，分析了971例患者的3028对评估结果。NSCAN活动分数随着RASS分数的增加而显着增加（Jonckheere-Terpstra测试，p<0.001)。每个RASS评分的活动评分的平均值为RASS-5,28.9;RASS-4,36.4;RASS-3,41.7;RASS-2,57.4;RASS-1,58.8;RASS0,62.6;RASS1,79.6;RASS2,106.5;和RASS3,118.7。
结论：NSCAN活动与改良的RASS躁动评分显著相关。关于躁动的实时NSCAN数据可能有助于及时干预以实现最佳症状控制。为了改善患有晚期谵妄的患者的预后，有必要对监测工具进行更多研究。
目的：研究使用非穿戴式传感器（NemuriSCAN[NSCAN]）测量的活动评分的客观测量是否与使用改良的里士满激动镇静量表（RASS）测量的激动水平相关。
方法：我们进行了单中心，prospective,在姑息治疗病房进行观察性研究，使用NSCAN测量活动评分，使用RASS评估躁动水平。RASS评分是由对NSCAN变量不知情的病房护士前瞻性测量的。创建了一个数据库，以在同一天晚上将RASS分数和活动分数配对。
结果：在观察期间，1209例患者住院，分析了971例患者的3028对评估结果。NSCAN活动分数随着RASS分数的增加而显着增加（Jonckheere-Terpstra测试，p<0.001)。每个RASS评分的活动评分的平均值为RASS-5,28.9;RASS-4,36.4;RASS-3,41.7;RASS-2,57.4;RASS-1,58.8;RASS0,62.6;RASS1,79.6;RASS2,106.5;和RASS3,118.7。
结论：NSCAN活动与改良的RASS躁动评分显著相关。关于躁动的实时NSCAN数据可能有助于及时干预以实现最佳症状控制。为了改善患有晚期谵妄的患者的预后，有必要对监测工具进行更多研究。
