Abstract：
The secondary sex ratio (SSR), defined as the ratio of male to female offspring at birth, has garnered significant scientific interest due to its potential impact on population dynamics and evolution. In recent years, there has been a growing concern regarding the potential consequences of environmental chemicals on the SSR, given their widespread exposure and potential enduring ramifications on the reproductive system. While SSR serves as an indicator of health, ongoing research and scientific inquiry are being conducted to explore the potential relationship between chemicals and offspring ratio. Although some studies have suggested a possible correlation, others have yielded inconclusive results, indicating that the topic is intricate and still needs to be elucidated. The precise mechanism by which chemical agents exert their influence on the SSR remains ambiguous, with disruption of the endocrine system being a prominent justification. In light of the complex interplay between chemical exposure and SSR, the present review aims to comprehensively examine and synthesize existing scientific literature to gain a deeper understanding of how specific chemical exposures may impact SSR. Insights into chemical hazards that shift SSR patterns or trends could guide prevention strategies, including legislative bans of certain chemicals, to minimize environmental and public health risks.
摘要：
次要性别比例(SSR)，定义为出生时男女后代的比例，由于其对种群动态和进化的潜在影响，已经获得了重大的科学兴趣。近年来,人们越来越担心环境化学品对SSR的潜在影响，考虑到它们的广泛暴露和对生殖系统的潜在持久影响。虽然SSR是健康的指标，正在进行的研究和科学调查，以探索化学品与后代比例之间的潜在关系。尽管一些研究表明了可能的相关性，其他人产生了不确定的结果，表明这个话题错综复杂，仍然需要阐明。化学试剂对SSR产生影响的确切机制仍然不明确，内分泌系统的中断是一个突出的理由。鉴于化学暴露和SSR之间复杂的相互作用，本综述旨在全面检查和综合现有的科学文献，以更深入地了解特定的化学暴露如何影响SSR。对改变SSR模式或趋势的化学危害的见解可以指导预防策略，包括某些化学品的立法禁令，将环境和公共卫生风险降至最低。
