关键词: Biomaterials Bioreactors Cultivated meat Edible biopolymers Scaffolds

Mesh : Biocompatible Materials Meat Animals Tissue Scaffolds Humans Tissue Engineering / methods Bioreactors In Vitro Meat

来  源:   DOI:10.1016/j.bioadv.2024.213897

Abstract:
The emergence of cultivated meat provides a sustainable and ethical alternative to traditional animal agriculture, highlighting its increasing importance in the food industry. Biomaterial scaffolds are critical components in cultivated meat production for enabling cell adhesion, proliferation, differentiation, and orientation. While there\'s extensive research on scaffolding biomaterials, applying them to cultivated meat production poses distinct challenges, with each material offering its own set of advantages and disadvantages. This review summarizes the most recent scaffolding biomaterials used in the last five years for cell-cultured meat, detailing their respective advantages and disadvantages. We suggest future research directions and provide recommendations for scaffolds that support scalable, cost-effective, and safe high-quality meat production. Additionally, we highlight commercial challenges cultivated meat faces, encompassing bioreactor design, cell culture mediums, and regulatory and food safety issues. In summary, this review provides a comprehensive guide and valuable insights for researchers and companies in the field of cultivated meat production.
摘要:
栽培肉的出现为传统动物农业提供了可持续和道德的替代方案,强调其在食品工业中的重要性。生物材料支架是培养肉生产中的关键组件,可实现细胞粘附。扩散,分化,和取向。虽然对支架生物材料有广泛的研究,将它们应用于种植肉类生产会带来明显的挑战,每种材料都有自己的优点和缺点。这篇综述总结了最近五年用于细胞培养肉的支架生物材料,详细说明它们各自的优缺点。我们建议未来的研究方向,并为支持可扩展的支架提供建议,成本效益高,和安全的优质肉类生产。此外,我们强调种植肉类面临的商业挑战,包括生物反应器设计,细胞培养基,以及监管和食品安全问题。总之,这篇综述为栽培肉类生产领域的研究人员和公司提供了全面的指导和有价值的见解。
公众号