Abstract：
Toxoplasmosis is one of the most common zoonotic parasitic diseases worldwide and is caused by Toxoplasma gondii. It is implicated in reproductive disorders in small ruminants. This study aims to determine, for the first time in Algeria, the seroprevalence and associated factors of T. gondii infection in goats. The study was conducted in four regions, Ghardaia, Laghouat and Djelfa, southern Algeria, and Jijel region, northern Algeria. A total of 92 blood samples were collected including 74 females and 18 males. All sera were tested using an enzyme-linked immunosorbent assay (ELISA) to detect the T. gondii antibodies. The presence of anti-T. gondii antibodies was detected in 35 out of 92 goats (38.04%) (95% CI: 31.64%-44.44%) and in all flocks (100%). Risk factors that have a significant influence on the seroprevalence of T. gondii infection are breed, regions, production system, presence of cats, clinics and abortion history. However, variables such as age and gender were note significantly associated with toxoplasma infection in goats. The highest seroprevalences of infection was observed in saanen (52.94%) (p<0.001) and cross-breed race (44%) (p<0.01) in comparison with other breeds. Regarding regions, Jijel and Laghouat were most infected with seroprevalences of 50% (p<0.001) and 40.91% (p<0.01), respectively. Animals in intensive production systems were most infected, showing a seroprevalence of 51.85%, in comparison with extensive (28.13%) and semi-intensive systems (36.36%) (p<0.001). The presence of cats in farms was significantly associated with high seroprevalence (44.64%) (p<0.001). The infection was more prevalent in previously aborted females (50%) than females that had never aborted (3.35%) (p<0.001)and animals that have diarrhoea or poor health (41.67%) were significantly more infected than healthy animals (37.50%) (p<0.01). Seroprevalence in males (38.89%) was very close to those in females (37.84%) (p>0.05). Age-related seroprevalence did not vary significantly (ranged from 36.37% to 40%) between the three age classes. These results indicate that goat toxoplasmosis is widespread in Algeria, and goats may represent a high risk of contamination for humans. This requires more attention during consumption of goat meat.
摘要：
弓形虫病是世界范围内最常见的人畜共患寄生虫病之一，由弓形虫引起。它与小反刍动物的生殖障碍有关。本研究旨在确定,第一次在阿尔及利亚，山羊弓形虫感染的血清阳性率及相关因素.这项研究在四个地区进行，Ghardaia,Laghouat和Djelfa,阿尔及利亚南部,和Jijel地区,阿尔及利亚北部共收集了92份血液样本，包括74名女性和18名男性。使用酶联免疫吸附测定(ELISA)检测所有血清以检测弓形虫抗体。反T的存在在92只山羊中的35只（38.04％）（95％CI：31.64％-44.44％）和所有羊群（100％）中检测到刚地抗体。对弓形虫感染的血清阳性率有重大影响的危险因素是品种，regions,生产系统,猫的存在，诊所和堕胎史。然而,注意,年龄和性别等变量与山羊弓形虫感染显著相关.与其他品种相比，在saanen（52.94％）（p<0.001）和杂交品种（44％）（p<0.01）中观察到最高的感染血清感染率。关于区域,Jijel和Laghouat感染最多，血清阳性率分别为50％（p<0.001）和40.91％（p<0.01），分别。密集生产系统中的动物感染最多，血清阳性率为51.85%，与广泛(28.13%)和半密集系统(36.36%)相比(p<0.001)。农场猫的存在与高血清阳性率（44.64％）显着相关（p<0.001）。先前流产的女性（50％）的感染比从未流产的女性（3.35％）的感染更为普遍（p<0.001），腹泻或健康状况不佳的动物（41.67％）的感染程度明显高于健康动物（37.50％）（p<0.01）。男性血清阳性率（38.89％）与女性（37.84％）非常接近（p>0.05）。三个年龄组之间与年龄相关的血清阳性率没有显着差异（范围为36.37％至40％）。这些结果表明，山羊弓形虫病在阿尔及利亚普遍存在，和山羊可能代表着人类污染的高风险。这在食用山羊肉期间需要更多的关注。
