METHODS: 191 FDG PET/CT studies of pediatric patients without malignant involvement of cervical lymph nodes were retrospectively reviewed. The maximal Standard Uptake Value in the hottest cervical lymph node (SUVmaxCLN), as well as demographic, technical and imaging variables were recorded. The predictive effect of those variables on SUVmaxCLN was estimated using linear regression models.
RESULTS: Increased FDG activity in cervical nodes was observed in 136/191 studies (71%). The mean SUVmaxCLN was 2.2 ± 1.3. Ipsilateral palatine tonsil SUVmax, mean liver uptake, and treatment status were all statistically significant predictors of SUVmaxCLN. However, in multivariate regression analysis, only ipsilateral palatine tonsil SUVmax was found to be significant. In addition, SUVmaxCLN was greater than the mean liver uptake in 50% of all studies. This proportion was higher in younger children, reaching 77% of studies of children younger than six years.
CONCLUSIONS: SUVmax in ipsilateral palatine tonsil is a strong predictor of the maximal uptake value of non-malignant cervical lymph nodes in children. The intensity of uptake in non-malignant cervical lymph nodes is frequently higher than liver uptake in children, and this tendency increases for younger patients.
UNASSIGNED: In the internal hospital registry under TRN 0209-22-HMO on date 23.04.2022.
方法:回顾性分析了191例没有颈部淋巴结恶性受累的儿童患者的FDGPET/CT研究。最热的颈淋巴结(SUVmaxCLN)的最大标准摄取值,以及人口统计,记录技术和成像变量.使用线性回归模型估计这些变量对SUVmaxCLN的预测作用。
结果:在136/191项研究中观察到宫颈淋巴结中FDG活性增加(71%)。平均SUVmaxCLN为2.2±1.3。同侧腭扁桃体SUVmax,平均肝脏摄取,和治疗状态都是SUVmaxCLN的统计学显著预测因子。然而,在多元回归分析中,只有同侧腭扁桃体SUVmax被发现是显著的。此外,在所有研究的50%中,SUVmaxCLN大于平均肝脏摄取。这个比例在年幼的孩子中更高,达到77%的六岁以下儿童的研究。
结论:同侧腭扁桃体的SUVmax是儿童非恶性颈部淋巴结最大摄取值的强预测指标。非恶性颈部淋巴结的摄取强度通常高于儿童的肝脏摄取,这种趋势在年轻患者中增加。
■在TRN0209-22-HMO下的内部医院登记处,日期为23.04.2022。