Abstract：
BACKGROUND: Anterior cruciate ligament (ACL) rupture is a debilitating condition and often requires surgery to restore joint stability. Common autografts used for reconstruction include patella tendon and hamstring tendons. The primary aim of this study was to evaluate the early to mid-term clinical outcomes of ACL reconstruction using validated patient-reported outcome measures (PROMs). The secondary aim was to compare clinical outcomes between patella tendon and hamstring tendon autografts. The tertiary aim was to compare clinical outcomes between males and females.
METHODS: Patients with an ACL rupture were evaluated before and after surgery using PROM scores which included Lysholm, Tegner, International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS), Short Form-12 Item (SF-12) and EQ-5D-5L.
RESULTS: A total of 87 patients were included in the study. All PROM scores significantly improved following surgery (p < 0.001) at a mean follow-up time of 28 months (range 12 to 88 months). The patella tendon subgroup (n = 27) had superior post-operative results as compared to the hamstring tendon subgroup (n = 60) for KOOS sport and recreation (p = 0.005), KOOS quality of life (p = 0.025), KOOS overall (p = 0.026), Tegner (p = 0.046) and IKDC (p = 0.021) scores. There was no significant difference of PROM scores between males (n = 60) and females (n = 27) (p > 0.05).
CONCLUSIONS: ACL reconstruction significantly improves clinical outcomes for patients with symptomatic instability consequent to ACL rupture. Overall, patella tendon autograft resulted in better clinical outcomes as compared to hamstring tendon autograft following surgery. Gender did not influence clinical outcome following ACL reconstruction.
METHODS: Patients with an ACL rupture were evaluated before and after surgery using PROM scores which included Lysholm, Tegner, International Knee Documentation Committee (IKDC), Knee Injury and Osteoarthritis Outcome Score (KOOS), Short Form-12 Item (SF-12) and EQ-5D-5L.
RESULTS: A total of 87 patients were included in the study. All PROM scores significantly improved following surgery (p < 0.001) at a mean follow-up time of 28 months (range 12 to 88 months). The patella tendon subgroup (n = 27) had superior post-operative results as compared to the hamstring tendon subgroup (n = 60) for KOOS sport and recreation (p = 0.005), KOOS quality of life (p = 0.025), KOOS overall (p = 0.026), Tegner (p = 0.046) and IKDC (p = 0.021) scores. There was no significant difference of PROM scores between males (n = 60) and females (n = 27) (p > 0.05).
CONCLUSIONS: ACL reconstruction significantly improves clinical outcomes for patients with symptomatic instability consequent to ACL rupture. Overall, patella tendon autograft resulted in better clinical outcomes as compared to hamstring tendon autograft following surgery. Gender did not influence clinical outcome following ACL reconstruction.
摘要：
背景：前交叉韧带（ACL）断裂是一种使人衰弱的疾病，通常需要手术来恢复关节稳定性。用于重建的常见自体移植物包括髌腱和绳肌腱。本研究的主要目的是使用经过验证的患者报告结果指标（PROMs）评估ACL重建的早期至中期临床结果。次要目的是比较髌骨肌腱和绳肌腱自体移植物的临床结果。第三目的是比较男性和女性之间的临床结果。
方法：使用包括Lysholm、Tegner,国际膝关节文献委员会(IKDC)膝关节损伤和骨关节炎结果评分（KOOS），简表-12项目(SF-12)和EQ-5D-5L。
结果：本研究共纳入87例患者。所有PROM评分在手术后显著改善(p<0.001),平均随访时间为28个月(范围12至88个月)。在KOOS运动和娱乐方面，髌骨肌腱亚组（n=27）的术后效果优于腿筋肌腱亚组（n=60）（p=0.005），KOOS生活质量（p=0.025），总体KOOS（p=0.026），Tegner(p=0.046)和IKDC(p=0.021)评分。男性（n=60）和女性（n=27）之间的PROM评分没有显着差异（p>0.05）。
结论：ACL重建可显著改善ACL破裂后症状不稳定患者的临床预后。总的来说,自体髌骨肌腱移植与自体绳肌腱移植相比，具有更好的临床效果。性别不影响ACL重建后的临床结果。
方法：使用包括Lysholm、Tegner,国际膝关节文献委员会(IKDC)膝关节损伤和骨关节炎结果评分（KOOS），简表-12项目(SF-12)和EQ-5D-5L。
结果：本研究共纳入87例患者。所有PROM评分在手术后显著改善(p<0.001),平均随访时间为28个月(范围12至88个月)。在KOOS运动和娱乐方面，髌骨肌腱亚组（n=27）的术后效果优于腿筋肌腱亚组（n=60）（p=0.005），KOOS生活质量（p=0.025），总体KOOS（p=0.026），Tegner(p=0.046)和IKDC(p=0.021)评分。男性（n=60）和女性（n=27）之间的PROM评分没有显着差异（p>0.05）。
结论：ACL重建可显著改善ACL破裂后症状不稳定患者的临床预后。总的来说,自体髌骨肌腱移植与自体绳肌腱移植相比，具有更好的临床效果。性别不影响ACL重建后的临床结果。
