Abstract:
<b><br>Introduction:</b> We report our experience in the treatment of parotid cancers by radiotherapy delivered with curative intent over a period of 10 years.</br> <b><br>Aim:</b> The aim of this study was to evaluate the therapeutic results and prognostic factors.</br> <b><br>Materials and methods:</b> This is a retrospective study of patients with parotid cancer treated with radiotherapy between 2008 and 2017 at the National Institute of Oncology in Rabat. Patients who received adjuvant or exclusive radiotherapy were included in this study. We performed a multivariate analysis for the factors related to locoregional control and overall survival.</br> <b><br>Results:</b> Initially, 74 patients (45 men and 29 women), at a median age of 57 years. were identified. At the time of diagnosis, 10 (13.6%), 36 (48.6%), and 28 (37.8%) patients were in stage II, III, and IVab, respectively. Sixty patients received adjuvant radiotherapy after parotidectomy and 14 patients received exclusive radiotherapy for an unresectable tumor. At 5 years, the rate of locoregional control and overall survival were 68.2% and 53.7%, respectively. Surgical resection and negative margins were significantly correlated with locoregional control. Lymph node involvement, unresectable tumors, high-grade histological types, and cystic adenoid carcinoma were significantly correlated with poor overall survival.</br> <b><br>Conclusions:</b> Acceptable long-term results are obtained with surgery combined with radiotherapy. Surgical resection remains essential for parotid cancer, given the disappointing results of treatment with radiotherapy alone.</br>.
摘要:
<b><br>简介:</b>我们报告了我们在10年期间通过放射治疗治疗腮腺癌的经验。</br><b>br>目的:</b>这项研究的目的是评估治疗结果和预后因素。</br><b><br>材料与方法:</b>这是拉巴特国立肿瘤研究所2008年至2017年间接受放疗的腮腺癌患者的回顾性研究。接受辅助或排他放疗的患者纳入本研究。我们对与局部控制和总体生存率相关的因素进行了多变量分析。</br><b><br>结果:</b>最初,74名患者(45名男性和29名女性),平均年龄为57岁。已确定。在诊断的时候,10(13.6%),36(48.6%),28例(37.8%)患者处于II期,III,还有IVab,分别。60例患者在腮腺切除术后接受了辅助放疗,14例患者因无法切除的肿瘤接受了独家放疗。在5年,局部控制率和总生存率分别为68.2%和53.7%,分别。手术切除和阴性切缘与局部控制显着相关。淋巴结受累,无法切除的肿瘤,高级组织学类型,囊性腺样癌与总生存率显著相关。</br><b><br>结论:</b>手术联合放疗可获得可接受的长期效果。手术切除对于腮腺癌仍然是必不可少的,考虑到单独放疗治疗的结果令人失望。</br>.