关键词: anterior eye segment axial eye length corneal curvature radius developmental size deficits prematurity

来  源:   DOI:10.1111/apa.17299

Abstract:
The renewed focus on eye growth in preterm-born children was primarily triggered by Danish cohort studies, including the Copenhagen Project, which focused on children born from 1959-1961. The retinotoxic effects of excessive oxygen on premature neonates had long been clarified and therapeutically adjusted for. Later, ultrasound oculometry and keratometry established that ocular size deficits, linked to development, also occurred in normally developing children, not just frail outliers. This indicated that general catch-up had not been achieved. This paper discusses whether one early segment of eye development does not occur in preterm, and here even in more robust neonates, without later compensation.
摘要:
对早产儿童眼睛生长的重新关注主要是由丹麦队列研究引发的。包括哥本哈根项目,重点关注1959-1961年出生的儿童。长期以来,人们已经阐明了过量氧气对早产儿的视网膜毒性作用,并对其进行了治疗调整。稍后,超声测量和角膜曲率确定了眼睛尺寸缺陷,与发展有关,也发生在正常发育的儿童中,不仅仅是脆弱的异常值。这表明尚未实现总体追赶。本文讨论了在早产中是否没有发生眼睛发育的早期阶段,即使在更健壮的新生儿中,没有以后的补偿。
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