PDF(Pubmed)
Abstract：
Marfan syndrome (MFS) is a rare hereditary connective tissue disorder with autosomal dominant inheritance associated with an increased risk of cardiovascular complications due to connective tissue fragility. Acute myocardial infarction during pregnancy is also a rare event associated with poor maternal and fetal outcomes. Herein, we report a case of a 30-year-old pregnant woman with a known history of MFS. The patient had been treated surgically for an ascending aorta aneurysm and mechanical prosthetic aortic valve repair. She presented at 12 weeks of gestation with severe chest pain, which proved to be acute myocardial infarction. This is believed to be the first case of this complex medical condition presented in the first trimester of pregnancy.
摘要：
马凡氏综合征（MFS）是一种罕见的遗传性结缔组织疾病，常染色体显性遗传与结缔组织脆性导致的心血管并发症风险增加有关。怀孕期间的急性心肌梗塞也是与不良的母体和胎儿结局相关的罕见事件。在这里，我们报告一例30岁孕妇,已知有MFS病史.该患者已接受升主动脉瘤和机械人工主动脉瓣修复手术治疗。她在妊娠12周时出现严重的胸痛，证明是急性心肌梗塞.这被认为是在怀孕的前三个月出现的这种复杂的医疗状况的第一例。
