关键词: colchicine treatment glenohumeral osteoarthritis gout disease medication for pain management shoulder joint pain

来  源:   DOI:10.7759/cureus.59181   PDF(Pubmed)

Abstract:
Osteoarthritis management primarily focuses on targeting pain. Conventional modalities for pain management include acetaminophen, non-steroidal anti-inflammatory drugs (NSAIDs), and intra-articular corticosteroid injections. However, these approaches may provide minimal pain relief and can be contraindicated for some patients, highlighting the ongoing need for alternative pain management. Colchicine, commonly used in the management of gout, has emerged as a potential option for pain management in osteoarthritis. There are implications of colchicine use for knee and hand osteoarthritis but remains inconclusive. In this context, we present a case of a 68-year-old diabetic woman with glenohumeral osteoarthritis and associated right shoulder pain. Due to minimal pain relief from previous treatments, the patient was given a combination trial of colchicine and acetaminophen for three months. After completion of this treatment, the patient experienced significant pain relief and improved functionality. The aim of this case is to highlight the efficacy of colchicine as a possible treatment option for managing shoulder pain in osteoarthritis.
摘要:
骨关节炎管理主要集中在靶向疼痛。疼痛管理的常规方法包括对乙酰氨基酚,非甾体抗炎药(NSAIDs),和关节内皮质类固醇注射。然而,这些方法可以提供最小的疼痛缓解,并且对某些患者可能是禁忌的,强调对替代疼痛管理的持续需求。秋水仙碱,常用于痛风的管理,已成为骨关节炎疼痛管理的潜在选择。使用秋水仙碱治疗膝关节和手部骨关节炎有一定的意义,但尚无定论。在这种情况下,我们介绍了一例68岁的糖尿病女性患者,患有肱骨关节炎和相关的右肩疼痛。由于以前治疗的疼痛缓解很小,患者接受了为期3个月的秋水仙碱和对乙酰氨基酚联合试验.治疗完成后,患者经历了显著的疼痛缓解和功能改善。这种情况的目的是强调秋水仙碱作为治疗骨关节炎中肩痛的可能治疗选择的功效。
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