Abstract：
OBJECTIVE: Patients with a septate uterus often have endometriosis, which can exacerbate their adverse pregnancy outcomes. We aimed to describe the clinical characteristics and treatment outcomes of patients with a septate uterus complicated by endometriosis.
METHODS: This retrospective study included patients who had a septate uterus complicated by endometriosis and were treated in Wuhan Tongji Hospital in the past 10 years. The characteristics of patients with a septate uterus and endometriosis were collected and described in terms of their preoperative and postoperative pregnancy outcomes.
RESULTS: There were 24 cases with a complete septate uterus and 49 cases with an incomplete septate uterus.Combinations of other malformations are more common in patients with complete septate uterus. In patients with a septate uterus, endometriosis often affected the ovaries, most commonly the left side (P < 0.001). Non-significant difference in the staging of endometriosis between complete and incomplete septate uterus (P= 0.812). Surgical treatment greatly improved the reproductive function and increased the live birth rate of patients with a septate uterus complicated by endometriosis (P < 0.001).
CONCLUSIONS: Compared to a septate uterus uncomplicated endometriosis, a septate uterus complicated by endometriosis significantly affects reproductive function. Surgical treatment can significantly improve the pregnancy outcomes of patients with a septate uterus and endometriosis. Clinicians should pay attention to timely diagnosing and treating these patients.
METHODS: This retrospective study included patients who had a septate uterus complicated by endometriosis and were treated in Wuhan Tongji Hospital in the past 10 years. The characteristics of patients with a septate uterus and endometriosis were collected and described in terms of their preoperative and postoperative pregnancy outcomes.
RESULTS: There were 24 cases with a complete septate uterus and 49 cases with an incomplete septate uterus.Combinations of other malformations are more common in patients with complete septate uterus. In patients with a septate uterus, endometriosis often affected the ovaries, most commonly the left side (P < 0.001). Non-significant difference in the staging of endometriosis between complete and incomplete septate uterus (P= 0.812). Surgical treatment greatly improved the reproductive function and increased the live birth rate of patients with a septate uterus complicated by endometriosis (P < 0.001).
CONCLUSIONS: Compared to a septate uterus uncomplicated endometriosis, a septate uterus complicated by endometriosis significantly affects reproductive function. Surgical treatment can significantly improve the pregnancy outcomes of patients with a septate uterus and endometriosis. Clinicians should pay attention to timely diagnosing and treating these patients.
摘要：
目的：子宫纵隔患者常有子宫内膜异位症，这可能会加剧他们的不良妊娠结局。我们旨在描述子宫纵隔合并子宫内膜异位症患者的临床特征和治疗结果。
方法：本研究纳入武汉市同济医院近10年收治的子宫纵隔合并子宫内膜异位症患者。收集子宫纵隔和子宫内膜异位症患者的特征，并根据其术前和术后妊娠结局进行描述。
结果：其中24例子宫完整，49例子宫不完整。其他畸形的组合在完全纵隔子宫的患者中更常见。子宫纵隔的患者，子宫内膜异位症经常影响卵巢，最常见的是左侧（P<0.001）。子宫内膜异位症在完全和不完全纵隔子宫间的分期差异无统计学意义(P=0.812)。手术治疗可显著改善子宫纵隔合并子宫内膜异位症患者的生育功能,提高活产率(P<0.001)。
结论：与无并发症的子宫内膜异位症相比，纵隔子宫并发子宫内膜异位症显著影响生殖功能。手术治疗可明显改善子宫纵隔合并子宫内膜异位症患者的妊娠结局。临床医生应注意及时诊断和治疗这些患者。
方法：本研究纳入武汉市同济医院近10年收治的子宫纵隔合并子宫内膜异位症患者。收集子宫纵隔和子宫内膜异位症患者的特征，并根据其术前和术后妊娠结局进行描述。
结果：其中24例子宫完整，49例子宫不完整。其他畸形的组合在完全纵隔子宫的患者中更常见。子宫纵隔的患者，子宫内膜异位症经常影响卵巢，最常见的是左侧（P<0.001）。子宫内膜异位症在完全和不完全纵隔子宫间的分期差异无统计学意义(P=0.812)。手术治疗可显著改善子宫纵隔合并子宫内膜异位症患者的生育功能,提高活产率(P<0.001)。
结论：与无并发症的子宫内膜异位症相比，纵隔子宫并发子宫内膜异位症显著影响生殖功能。手术治疗可明显改善子宫纵隔合并子宫内膜异位症患者的妊娠结局。临床医生应注意及时诊断和治疗这些患者。
