Abstract：
Guaifenesin, a widely used ingredient in over-the-counter cough and cold medications, has been a subject of debate regarding its efficacy in treating respiratory conditions. Despite its historical use and US Food and Drug Administration approval, recent studies have questioned its claimed expectorant effect and its effectiveness in managing symptoms. This article examines the available evidence, highlighting the lack of significant benefits over placebo for upper respiratory disease. The rationale for clinical use is examined alongside the potential downside and alternatives to recommending guaifenesin as a treatment option.
摘要：
愈创甘油醚,一种广泛用于非处方咳嗽和感冒药的成分，关于其治疗呼吸系统疾病的功效一直是争论的话题。尽管它的历史用途和美国食品和药物管理局的批准，最近的研究质疑其声称的祛痰效果及其在控制症状方面的有效性。这篇文章研究了现有的证据，强调上呼吸道疾病与安慰剂相比缺乏显著的益处。研究了临床使用的基本原理，以及推荐愈创木醚作为治疗选择的潜在缺点和替代品。
