Abstract：
OBJECTIVE: To identify predictors of sexual satisfaction in patients with advanced cancer and their family caregivers.
METHODS: Cross-sectional study using baseline survey data from a randomized controlled trial in six European countries. Patients with advanced cancer and their family caregiver completed measures on sexual satisfaction (one item from Functional Assessment of Cancer Therapy - General questionnaire for patients and Caregiver Quality of Life Index-Cancer scale for family caregivers) and health-related characteristics. Multivariable linear regressions were performed for all predictors (identified based on literature) with sexual satisfaction as dependent variable.
RESULTS: The sample comprised 431 patient-family caregiver dyads. Patients with prostate or gynecological cancer reported lower sexual satisfaction (respectively B = -0.267 95% CI: -1.674, -0.594 and B = -0.196, 95% CI -2.103, -0.452). Higher emotional (B = 0.278, 95% CI 0.024, 0.057) physical (B = 0.305, 95% CI 0.012, 0.025) and social functioning (B = 0.151, 95% CI 0.001, 0.013), global health (B = 0.356, 95% CI 0.007, 0.013) and social wellbeing (B = 0.161, 95% CI 0.013, 0.082) among patients were associated with higher sexual satisfaction. Among family caregivers, sexual satisfaction was lower with increased age (B = -0.142, 95% CI -0.022, -0.004). Higher emotional functioning (B = 0.027, 95% CI 0.011, 0.043) and quality of life (B = 0.165, 95% CI -0.165, 0.716) were associated with higher sexual satisfaction in family caregivers.
CONCLUSIONS: The results underscore that sexual wellbeing of patients and family caregivers is related to health related factors in physical, emotional, and social domains. Patients and family caregivers could benefit from a dyadic approach to address sexual wellbeing.
METHODS: Cross-sectional study using baseline survey data from a randomized controlled trial in six European countries. Patients with advanced cancer and their family caregiver completed measures on sexual satisfaction (one item from Functional Assessment of Cancer Therapy - General questionnaire for patients and Caregiver Quality of Life Index-Cancer scale for family caregivers) and health-related characteristics. Multivariable linear regressions were performed for all predictors (identified based on literature) with sexual satisfaction as dependent variable.
RESULTS: The sample comprised 431 patient-family caregiver dyads. Patients with prostate or gynecological cancer reported lower sexual satisfaction (respectively B = -0.267 95% CI: -1.674, -0.594 and B = -0.196, 95% CI -2.103, -0.452). Higher emotional (B = 0.278, 95% CI 0.024, 0.057) physical (B = 0.305, 95% CI 0.012, 0.025) and social functioning (B = 0.151, 95% CI 0.001, 0.013), global health (B = 0.356, 95% CI 0.007, 0.013) and social wellbeing (B = 0.161, 95% CI 0.013, 0.082) among patients were associated with higher sexual satisfaction. Among family caregivers, sexual satisfaction was lower with increased age (B = -0.142, 95% CI -0.022, -0.004). Higher emotional functioning (B = 0.027, 95% CI 0.011, 0.043) and quality of life (B = 0.165, 95% CI -0.165, 0.716) were associated with higher sexual satisfaction in family caregivers.
CONCLUSIONS: The results underscore that sexual wellbeing of patients and family caregivers is related to health related factors in physical, emotional, and social domains. Patients and family caregivers could benefit from a dyadic approach to address sexual wellbeing.
摘要：
目的：确定晚期癌症患者及其家庭照顾者性生活满意度的预测因素。
方法：使用来自六个欧洲国家的随机对照试验的基线调查数据进行横断面研究。晚期癌症患者及其家庭照顾者完成了性满意度的测量（来自癌症治疗功能评估-患者一般问卷和照顾者生活质量指数-家庭照顾者癌症量表的一项）和健康相关特征。以性满意度为因变量，对所有预测因子（根据文献确定）进行多变量线性回归。
结果：样品包括431个患者-家庭护理人员二分体。前列腺癌或妇科癌症患者的性满意度较低（分别为B=-0.26795％CI：-1.674，-0.594和B=-0.196，95％CI-2.103，-0.452）。较高的情绪（B=0.278，95％CI0.024，0.057），身体（B=0.305，95％CI0.012，0.025）和社会功能（B=0.151，95％CI0.001，0.013），患者的全球健康(B=0.356,95%CI0.007,0.013)和社会福祉(B=0.161,95%CI0.013,0.082)与较高的性满意度相关.在家庭照顾者中，性满意度随着年龄的增加而降低(B=-0.142,95%CI-0.022,-0.004).较高的情绪功能（B=0.027，95％CI0.011，0.043）和生活质量（B=0.165，95％CI-0.165，0.716）与家庭照顾者较高的性满意度相关。
结论：结果强调，患者和家庭照顾者的性健康与身体健康相关因素有关，情感,和社会领域。患者和家庭护理人员可以从解决性健康的二元方法中受益。
方法：使用来自六个欧洲国家的随机对照试验的基线调查数据进行横断面研究。晚期癌症患者及其家庭照顾者完成了性满意度的测量（来自癌症治疗功能评估-患者一般问卷和照顾者生活质量指数-家庭照顾者癌症量表的一项）和健康相关特征。以性满意度为因变量，对所有预测因子（根据文献确定）进行多变量线性回归。
结果：样品包括431个患者-家庭护理人员二分体。前列腺癌或妇科癌症患者的性满意度较低（分别为B=-0.26795％CI：-1.674，-0.594和B=-0.196，95％CI-2.103，-0.452）。较高的情绪（B=0.278，95％CI0.024，0.057），身体（B=0.305，95％CI0.012，0.025）和社会功能（B=0.151，95％CI0.001，0.013），患者的全球健康(B=0.356,95%CI0.007,0.013)和社会福祉(B=0.161,95%CI0.013,0.082)与较高的性满意度相关.在家庭照顾者中，性满意度随着年龄的增加而降低(B=-0.142,95%CI-0.022,-0.004).较高的情绪功能（B=0.027，95％CI0.011，0.043）和生活质量（B=0.165，95％CI-0.165，0.716）与家庭照顾者较高的性满意度相关。
结论：结果强调，患者和家庭照顾者的性健康与身体健康相关因素有关，情感,和社会领域。患者和家庭护理人员可以从解决性健康的二元方法中受益。
