Abstract:
The association between Medically Assisted Reproduction (MAR) and thromboembolic complications has been reported widely in multiple published studies. Although venous thromboembolism (VTE) is not thought to be a common complication of MAR, it is associated with high morbidity and is often preventable. Since VTE usually occurs after completion of MAR treatment and is often managed outside of the treating fertility unit, these complications are likely to be underreported and there may be limited awareness of the risks among clinicians. As we continue to see a rise in the total number of MAR treatment cycles, particularly in women over 40 years of age, along with a steady increase in the number of fertility preservation cycles for both medical and social indications, it is likely that we will see an increase in absolute numbers of VTE complications. Currently, there is a lack of management guidance and reporting of VTE events associated with assisted conception treatment. The aim of this guidance is to provide clinicians with information on VTE risk factors, guidance on assessing VTE risk and the best practice recommendations on risk reducing strategies for individuals at risk of VTE undergoing ovarian stimulation and embryo transfer cycles.
摘要:
医学辅助生殖(MAR)与血栓栓塞并发症之间的关联已在多项已发表的研究中得到广泛报道。尽管静脉血栓栓塞症(VTE)不被认为是MAR的常见并发症,它与高发病率相关,通常是可以预防的。由于VTE通常在MAR治疗完成后发生,并且通常在治疗生育单位之外进行管理,这些并发症可能被低估,临床医生对风险的认识可能有限.随着我们继续看到MAR治疗周期总数的增加,尤其是40岁以上的女性,随着医学和社会指征的生育保存周期数量的稳步增加,我们很可能会看到VTE并发症的绝对数量增加.目前,缺乏与辅助受孕治疗相关的VTE事件的管理指导和报告.本指南的目的是为临床医生提供有关VTE危险因素的信息,关于评估VTE风险的指南和对有VTE风险的个体进行卵巢刺激和胚胎移植周期的风险降低策略的最佳实践建议.