PDF(Pubmed)
Abstract：
UNASSIGNED: The overall diagnostic value of fine-needle aspiration (FNA) is not as excellent as that of core needle biopsy (CNB). Limited research has investigated small cervical lymph nodes inaccessible to ultrasound-guided CNB due to technical challenges associated with their small size. Therefore, this study aimed to evaluate the accuracy of ultrasound-guided FNA in determining the etiology of small cervical lymph nodes.
UNASSIGNED: A retrospective analysis was conducted on patients who underwent FNA between May 2018 and May 2021 at our hospital. Cytological, histopathological, and clinical follow-up data were analyzed. The diagnostic yield of FNA was assessed based on sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy calculations.
UNASSIGNED: This study included 505 patients, each with a small cervical lymph node under evaluation (total number of lymph nodes: 505). The average maximal diameter of the lymph nodes was 14.6 ± 6.2 mm. According to the Sydney system, the cytology results were as follows: Category I in 26 lymph nodes (5.1 %); Category II in 269 (53.3 %); Category III in 35 (6.9 %); Category IV in 17 (3.4 %); and Category V in 158 (31.3 %). We identified 212 malignant cases (203 metastases and 9 lymphomas) and 293 benign lymph nodes. FNA achieved high sensitivity (88.8 %), specificity (99.6 %), PPV (99.4 %), NPV (91.8 %), and overall accuracy (94.8 %) in determining the etiology of small cervical lymph nodes.
UNASSIGNED: FNA cytology is suitable for small lesions inaccessible by CNB and provides a diagnostic basis for implementing clinically appropriate treatment measures.
UNASSIGNED: A retrospective analysis was conducted on patients who underwent FNA between May 2018 and May 2021 at our hospital. Cytological, histopathological, and clinical follow-up data were analyzed. The diagnostic yield of FNA was assessed based on sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy calculations.
UNASSIGNED: This study included 505 patients, each with a small cervical lymph node under evaluation (total number of lymph nodes: 505). The average maximal diameter of the lymph nodes was 14.6 ± 6.2 mm. According to the Sydney system, the cytology results were as follows: Category I in 26 lymph nodes (5.1 %); Category II in 269 (53.3 %); Category III in 35 (6.9 %); Category IV in 17 (3.4 %); and Category V in 158 (31.3 %). We identified 212 malignant cases (203 metastases and 9 lymphomas) and 293 benign lymph nodes. FNA achieved high sensitivity (88.8 %), specificity (99.6 %), PPV (99.4 %), NPV (91.8 %), and overall accuracy (94.8 %) in determining the etiology of small cervical lymph nodes.
UNASSIGNED: FNA cytology is suitable for small lesions inaccessible by CNB and provides a diagnostic basis for implementing clinically appropriate treatment measures.
摘要：
■细针穿刺（FNA）的总体诊断价值不如芯针活检（CNB）。有限的研究已经调查了由于与小尺寸相关的技术挑战而无法进入超声引导的CNB的小颈淋巴结。因此,本研究旨在评估超声引导下FNA确定颈部小淋巴结病因的准确性。
■对2018年5月至2021年5月在我院接受FNA的患者进行了回顾性分析。细胞学,组织病理学,并对临床随访资料进行分析。根据灵敏度评估FNA的诊断率，特异性，阳性预测值(PPV)，负预测值(NPV)，和精确计算。
■这项研究包括505名患者，每个有一个小的颈部淋巴结评估（淋巴结总数：505）。淋巴结的平均最大直径为14.6±6.2mm。根据悉尼系统，细胞学结果如下:26个淋巴结中的I类(5.1%);269个中的II类(53.3%);35个中的III类(6.9%);17个中的IV类(3.4%);158个中的V类(31.3%).我们确定了212例恶性病例（203例转移和9例淋巴瘤）和293例良性淋巴结。FNA实现了高灵敏度（88.8%），特异性（99.6%），PPV（99.4%），净现值（91.8%），以及确定颈部小淋巴结病因的总体准确性（94.8％）。
■FNA细胞学检查适用于CNB无法进入的小病灶，为实施临床上适当的治疗措施提供了诊断依据。
■对2018年5月至2021年5月在我院接受FNA的患者进行了回顾性分析。细胞学,组织病理学,并对临床随访资料进行分析。根据灵敏度评估FNA的诊断率，特异性，阳性预测值(PPV)，负预测值(NPV)，和精确计算。
■这项研究包括505名患者，每个有一个小的颈部淋巴结评估（淋巴结总数：505）。淋巴结的平均最大直径为14.6±6.2mm。根据悉尼系统，细胞学结果如下:26个淋巴结中的I类(5.1%);269个中的II类(53.3%);35个中的III类(6.9%);17个中的IV类(3.4%);158个中的V类(31.3%).我们确定了212例恶性病例（203例转移和9例淋巴瘤）和293例良性淋巴结。FNA实现了高灵敏度（88.8%），特异性（99.6%），PPV（99.4%），净现值（91.8%），以及确定颈部小淋巴结病因的总体准确性（94.8％）。
■FNA细胞学检查适用于CNB无法进入的小病灶，为实施临床上适当的治疗措施提供了诊断依据。
