PDF(Pubmed)
Abstract：
Surgical site infections (SSIs) following open reduction and internal fixation (ORIF) of ankle fractures can lead to significant disability. This case report emphasizes a unique instance of SSI caused by Corynebacterium simulans, following ORIF of a trimalleolar ankle fracture in a 55-year-old female patient. To our knowledge, this is the first reported case of C. simulans infection after ORIF in the literature. The pathogen was detected after surgical debridement, removal and sonication of the hardware, and identified through matrix assisted laser desorption/ionization-time of flight mass spectrometry (MALDI-TOF MS) and 16S rRNA gene sequencing. Specific intravenous antibiotic regimen was administered for a total duration of 4 weeks. During the 12th month follow-up, the patient presented no signs of infection and an excellent clinical outcome. This case report underscores the need for alertness regarding atypical pathogens in postoperative complications and the critical role of precise microbial diagnosis in managing rare orthopaedic infections.
摘要：
踝关节骨折切开复位内固定（ORIF）后的手术部位感染（SSIs）可导致严重的残疾。此病例报告强调了由模拟棒状杆菌引起的SSI的一个独特实例，一名55岁女性患者三踝骨折ORIF后。据我们所知,这是文献中首次报道的ORIF后C.simulans感染病例.在手术清创术后检测到病原体，硬件的拆卸和超声处理，并通过基质辅助激光解吸/电离飞行时间质谱（MALDI-TOFMS）和16SrRNA基因测序进行鉴定。特定的静脉内抗生素方案的总持续时间为4周。在第12个月的随访中，患者未出现感染迹象,临床结局良好.此病例报告强调需要警惕术后并发症中的非典型病原体，以及精确的微生物诊断在管理罕见的骨科感染中的关键作用。
