关键词: medical practice oncology photodynamic therapy (PDT) photosensitizers treatment cancer

来  源:   DOI:10.3389/fonc.2024.1373263   PDF(Pubmed)

Abstract:
Cancer therapy, especially for tumors near sensitive areas, demands precise treatment. This review explores photodynamic therapy (PDT), a method leveraging photosensitizers (PS), specific wavelength light, and oxygen to target cancer effectively. Recent advancements affirm PDT\'s efficacy, utilizing ROS generation to induce cancer cell death. With a history spanning over decades, PDT\'s dynamic evolution has expanded its application across dermatology, oncology, and dentistry. This review aims to dissect PDT\'s principles, from its inception to contemporary medical applications, highlighting its role in modern cancer treatment strategies.
摘要:
癌症治疗,尤其是敏感区域附近的肿瘤,需要精确的治疗。这篇综述探讨了光动力疗法(PDT),一种利用光敏剂(PS)的方法,特定波长的光,和氧气有效靶向癌症。最近的进步肯定了PDT的疗效,利用ROS产生诱导癌细胞死亡。有着几十年的历史,PDT的动态进化扩展了其在皮肤科的应用,肿瘤学,和牙科。这篇综述旨在剖析PDT的原理,从成立到当代医学应用,强调其在现代癌症治疗策略中的作用。
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