Abstract:
During outdoor work in April 2022, a 48-year-old man was stabbed by a tree branch and underwent intraocular foreign body extraction and repair of the scleral wound with sutures and amniotic membrane graft at a local hospital. Steroid therapy with prednisone was prescribed after a diagnosis of uveitis. Vitrectomy was performed in June 2023; a fungal culture was positive, and ITS sequencing identified the organism as Paradictyoarthrinium diffractum. Empiric antifungal therapy did not have an effect, and, because of deterioration of the condition, the left eye was enucleated in October 2023. P. diffractum is a mangrove host-specific saprophytic fungus that has not been reported in humans.
摘要:
在2022年4月的户外工作中,一名48岁的男子被树枝刺伤,并在当地医院接受了眼内异物取出和缝线和羊膜移植修复巩膜伤口。诊断为葡萄膜炎后,使用泼尼松进行类固醇治疗。2023年6月进行了玻璃体切除术;真菌培养呈阳性,ITS测序将该生物鉴定为衍射副齿。经验性抗真菌治疗没有效果,and,因为病情恶化,左眼于2023年10月摘除.P.衍射是一种红树林宿主特异性腐生真菌,尚未在人类中报道。