关键词: Antibacterial activity Haematological parameters Weathered polyethylene microplastics Zebrafish

Mesh : Animals Microplastics / toxicity Water Pollutants, Chemical / toxicity Polyethylene / toxicity Male Zebrafish / immunology Female Muramidase Immunomodulation / drug effects

来  源:   DOI:10.1016/j.etap.2024.104478

Abstract:
Microplastics are pollutants of emerging concern and the aquatic biota consumes microplastics (MPs), which has a range of toxicological and environmental effects on aquatic organisms that are not the intended targets. The current study looked into how weathered polyethylene (wPE) MPs affected Danio albolineatus immunological and haematological markers. In this experiment, fish of both sexes were placed in control and exposure groups, and they were exposed for 40 d at the sublethal level (1 μg L-1) of fragmented wPE, which contained 1074 ± 52 MPs per litre. Similarly, fish exposed to wPE MPs showed significant modifications in lysozyme, antimicrobial, and antiprotease activity, as well as differential counts. Results of the present study show that the male fish were more susceptible than female fish after 40 d of chronic exposure. Further studies are needed to ascertain how the innate and humoral immune systems of the fish respond to MPs exposure.
摘要:
微塑料是新兴关注的污染物,水生生物群消耗微塑料(MPs),对不是预期目标的水生生物有一系列毒理学和环境影响。当前的研究调查了风化聚乙烯(wPE)MPs如何影响Danioalbolineatus免疫学和血液学标志物。在这个实验中,将两性的鱼置于对照组和暴露组,他们在亚致死水平(1μgL-1)的碎片化wPE暴露40天,每升含1074±52议员。同样,暴露于WPEMPs的鱼在溶菌酶中显示出显着的修饰,抗菌,和抗蛋白酶活性,以及微分计数。本研究的结果表明,在慢性暴露40d后,雄性鱼比雌性鱼更易感。需要进一步的研究来确定鱼的先天和体液免疫系统如何对MP暴露做出反应。
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