Abstract：
It is not yet understood whether, and to what extent, craniosynostosis impacts the development of Attention Deficit/Hyperactivity Disorder (ADHD). This PRISMA compliant and PROSPERO pre-registered (ID: CRD42023458640) systematic review and meta-analysis examines the association of single-suture, non-syndromic craniosynostosis with ADHD and inattention/hyperactivity symptoms. Data from 17 independent studies (Nparticipants = 2,389; Mage = 7.3 years) were analyzed, taking into consideration suture location, surgical status, age, and measures administered, where feasible. Few differences were found between cases and controls, but some studies reported high symptom levels. Additional research is required utilizing larger sample sizes and more comprehensive assessment of ADHD.
摘要：
目前尚不清楚,在多大程度上，颅骨融合影响注意力缺陷/多动障碍（ADHD）的发展。此PRISMA兼容和PROSPERO预注册（ID：CRD42023458640）系统评价和荟萃分析检查了单缝线的关联，伴有ADHD和注意力不集中/多动症状的非综合征性颅骨融合。分析了来自17项独立研究（Nparticipators=2,389;Mage=7.3年）的数据，考虑到缝合位置，手术状态,年龄,和管理的措施，在可行的地方。病例和对照之间几乎没有差异，但是一些研究报告称症状水平很高。需要使用更大的样本量和更全面的ADHD评估进行其他研究。
