PDF(Pubmed)
Abstract：
Amyloidosis is the condition when starch-like misfolded proteins form insoluble fibrils that deposit in tissues and cause dysfunction. Cardiac amyloidosis occurs due to the deposition of amyloid fibrils at the cardiac level and is an important cause of heart failure. This case reveals a patient with significant heart failure and arrhythmia, which later on turned out to be caused by cardiac amyloidosis. While regarded as a rare disease in practice, in retrospect, there are a lot of signs and imaging indicators, particularly in echocardiography that warrant an investigation of cardiac amyloidosis. In this case review, red flags in echocardiography that should endorse further testing for underlying cardiac amyloidosis are highlighted.
摘要：
淀粉样变性是当淀粉样错误折叠的蛋白质形成沉积在组织中并导致功能障碍的不溶性原纤维时的病症。心脏淀粉样变性是由于淀粉样原纤维在心脏水平的沉积而发生的，并且是心力衰竭的重要原因。这个病例显示有严重心力衰竭和心律失常的病人,后来证明是由心脏淀粉样变引起的。虽然在实践中被认为是一种罕见的疾病，回想起来，有很多迹象和成像指标，特别是在需要对心脏淀粉样变进行调查的超声心动图中。在这种情况下，审查，强调了超声心动图中的危险信号，这些危险信号应支持对潜在的心脏淀粉样变性的进一步检测。
