PDF(Pubmed)
Abstract：
The central giant cell granuloma displays a varied biologic behaviour ranging from simple reactive lesions to aggressive neoplasms. The pathogenicity still remains enigmatic and needs to be differentiated from other giant cell containing lesions. Both maxilla and mandible are affected and 80% involve the region anterior to the first premolar region. CGCL arises centrally within bone, whereas PGCG is a gingival soft tissue lesion. Clinical and radiographic correlation is required to rule out a peripheral giant cell granuloma. The case described here was a rare presentation of a large epulis clinically with involvement of maxilla radiographically and was histologically diagnosed as a central giant cell lesion.
摘要：
中央巨细胞肉芽肿表现出多种生物学行为，从简单的反应性病变到侵袭性肿瘤。致病性仍然是神秘的，需要与其他含有巨细胞的病变区分开来。上颌骨和下颌骨都受到影响，并且80％涉及第一前磨牙区域之前的区域。CGCL出现在骨中央，而PGCG是牙龈软组织病变。临床和影像学相关性需要排除周围性巨细胞肉芽肿。此处描述的病例是临床上罕见的大上皮，上颌骨在影像学上受累，在组织学上被诊断为中央巨细胞病变。
