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Abstract：
Introduction Lymphadenopathy, characterized by the enlargement of lymph nodes, is a common concern encountered by physicians in outpatient settings. It is deemed significant and warrants evaluation due to the diverse range of potential causes, ranging from treatable infections to incurable metastatic malignancies. Fine needle aspiration cytology (FNAC) emerges as a crucial tool in addressing these concerns, acknowledged for its rapid diagnostic capabilities, simplicity, accuracy, and minimal invasiveness. Objectives This retrospective study aims to characterize the spectrum of lymphadenopathy cases observed in a tertiary care center over a specified period, shedding light on the prevalence, etiology, and clinical outcomes associated with this condition. Methods Electronic medical records of patients presenting with lymphadenopathy to the tertiary care center between May 2021 and June 2023 were reviewed. Data on patient demographics, clinical presentation, imaging findings, and cytopathological and histopathological diagnoses were analyzed. Results A total of 300 cases of lymphadenopathy were identified during the study period. The study population exhibited a diverse range of age groups, with a slight predilection for the age range of 11-20 years. The most common sites of lymphadenopathy were in the cervical group, and the predominant clinical presentations included tender lymph nodes and fever. Etiologically, infectious causes, such as accounted for the majority of cases, followed by inflammatory and neoplastic etiologies. Notably, 2.6 % of cases presented with non-specific lymphadenopathy, warranting further investigation. Diagnostic modalities, including imaging studies and histopathological examinations, played a crucial role in establishing accurate diagnoses. The study also highlights the challenges in differentiating benign from malignant lymphadenopathy, emphasizing the need for a comprehensive diagnostic approach. Conclusion This study provides a comprehensive overview of the lymphadenopathy spectrum in a tertiary care center, emphasizing the importance of a multidisciplinary approach for accurate diagnosis and management. The findings contribute to our understanding of the epidemiology and etiological patterns of lymphadenopathy, guiding clinicians in optimizing patient care and outcomes in a tertiary healthcare setting.
摘要：
简介淋巴结肿大,以淋巴结肿大为特征，是门诊医生常见的问题。由于潜在原因的不同，它被认为是重要的，值得评估，从可治疗的感染到无法治愈的转移性恶性肿瘤。细针穿刺细胞学（FNAC）是解决这些问题的重要工具，承认其快速诊断能力，简单，准确度,和最小的侵入性。目的这项回顾性研究旨在描述特定时期在三级护理中心观察到的淋巴结病病例的频谱。揭示患病率，病因学,以及与这种情况相关的临床结果。方法对2021年5月至2023年6月到三级护理中心就诊的淋巴结病患者的电子病历进行回顾。患者人口统计数据，临床表现,影像学发现，分析了细胞病理学和组织病理学诊断。结果在研究期间共发现300例淋巴结肿大。研究人群表现出不同的年龄组，对11-20岁的年龄范围略有偏爱。淋巴结肿大最常见的部位是宫颈组，主要临床表现包括淋巴结肿大和发热。病因学上,传染性原因,例如占大多数情况，其次是炎症和肿瘤病因。值得注意的是,2.6%的病例表现为非特异性淋巴结病，保证进一步调查。诊断模式，包括影像学检查和组织病理学检查，在建立准确的诊断中起着至关重要的作用。该研究还强调了区分良性和恶性淋巴结病的挑战，强调需要全面的诊断方法。结论本研究全面概述了三级护理中心的淋巴结病谱，强调多学科方法对准确诊断和管理的重要性。这些发现有助于我们了解淋巴结病的流行病学和病因学模式，指导临床医生在三级医疗保健环境中优化患者护理和结果。
