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Abstract：
BACKGROUND: In Nigeria, 97% of the population is at risk of contracting malaria. It is transmitted by female Anopheles mosquitoes carrying the Plasmodium parasite and can be lethal. An estimated 55 million illnesses and 80,000 deaths per year result from it. Children under five are more likely to contract malaria. Efforts to control malaria in Nigeria include indoor residual spraying, insecticide-treated bed nets, and quick detection and treatment of confirmed cases with effective antimalarial medications. These attempts have been impeded by limited healthcare access, poor financing, and drug-resistant parasites. Thus, the study of the relationship between malaria complications and housing for children under five is essential.
METHODS: The Demographic and Health Survey (DHS) Malaria Indicator Survey (MIS) 2021, a nationally representative data set from developing countries on population and health, was used for this study. A sample size of 13,727 was employed (n=13,727). Logistic regression analyses were conducted to test the association between the type of place of residence and malaria complications (outcome).
RESULTS: Overall, 4.2% (n=570, weight HV005) of participants in the sample reported malaria complications. The results of the logistic regression revealed that children residing in urban settlements (aOR 0.37, 95% CI 0.37-0.37, p-value <0.001), children from the poorest class families (aOR 11.63, 95% CI 1.62-1.63, p-value 0.004), children from poorer class families (aOR 7.56, 95% CI 7.55-7.57, p-value <0.001), children from middle-class families (aOR 4.05, 95% CI 4.03-9.06, p-value <0.001), children from richer class families (aOR 1.22, 95% CI 2.21-2.23, p-value <0.001), children of mothers with primary education (aOR 0.42, 95% CI 2.32-4.112, p-value 0.001), children of mothers with secondary education (aOR 0.24, 95% CI 3.21-3.22, p-value <0.001), children of mothers with higher education (aOR 0.08, 95% CI 0.72-0.80, p-value <0.001), and children of the female gender (aOR 0.65, 95% CI 0.65-0.66, p-value <0.001) are all associated with severe malaria complications.
CONCLUSIONS: In conclusion, the study examined malaria complications in Nigerian children under five by residency. The findings imply that rural children are more likely to have serious malaria complications than urban children. This emphasizes the necessity for targeted malaria therapies in rural areas with limited healthcare access.
METHODS: The Demographic and Health Survey (DHS) Malaria Indicator Survey (MIS) 2021, a nationally representative data set from developing countries on population and health, was used for this study. A sample size of 13,727 was employed (n=13,727). Logistic regression analyses were conducted to test the association between the type of place of residence and malaria complications (outcome).
RESULTS: Overall, 4.2% (n=570, weight HV005) of participants in the sample reported malaria complications. The results of the logistic regression revealed that children residing in urban settlements (aOR 0.37, 95% CI 0.37-0.37, p-value <0.001), children from the poorest class families (aOR 11.63, 95% CI 1.62-1.63, p-value 0.004), children from poorer class families (aOR 7.56, 95% CI 7.55-7.57, p-value <0.001), children from middle-class families (aOR 4.05, 95% CI 4.03-9.06, p-value <0.001), children from richer class families (aOR 1.22, 95% CI 2.21-2.23, p-value <0.001), children of mothers with primary education (aOR 0.42, 95% CI 2.32-4.112, p-value 0.001), children of mothers with secondary education (aOR 0.24, 95% CI 3.21-3.22, p-value <0.001), children of mothers with higher education (aOR 0.08, 95% CI 0.72-0.80, p-value <0.001), and children of the female gender (aOR 0.65, 95% CI 0.65-0.66, p-value <0.001) are all associated with severe malaria complications.
CONCLUSIONS: In conclusion, the study examined malaria complications in Nigerian children under five by residency. The findings imply that rural children are more likely to have serious malaria complications than urban children. This emphasizes the necessity for targeted malaria therapies in rural areas with limited healthcare access.
摘要：
背景：在尼日利亚，97%的人口面临感染疟疾的风险。它由携带疟原虫寄生虫的雌性按蚊传播，可能致命。据估计，每年有5500万种疾病和8万人死亡。五岁以下的儿童更容易感染疟疾。尼日利亚控制疟疾的努力包括室内残留喷洒，杀虫剂处理过的蚊帐,以及使用有效的抗疟药物快速检测和治疗确诊病例。这些尝试受到了有限的医疗保健服务的阻碍，融资不佳，和耐药寄生虫.因此，研究疟疾并发症与五岁以下儿童住房之间的关系至关重要。
方法：人口与健康调查（DHS）疟疾指标调查（MIS）2021，这是发展中国家人口与健康的国家代表性数据集，用于这项研究。采用13,727的样品大小(n=13,727)。进行了Logistic回归分析，以测试居住地类型与疟疾并发症（结果）之间的关联。
结果：总体而言，样本中有4.2%(n=570,体重HV005)的参与者报告了疟疾并发症。Logistic回归结果显示，居住在城市住区的儿童（aOR0.37，95％CI0.37-0.37，p值<0.001），来自最贫困家庭的儿童(aOR11.63，95%CI1.62-1.63，p值0.004)，来自贫困家庭的儿童（aOR7.56，95%CI7.55-7.57，p值<0.001），来自中产阶级家庭的儿童（aOR4.05，95%CI4.03-9.06，p值<0.001），来自富裕阶层家庭的儿童(aOR1.22，95%CI2.21-2.23，p值<0.001)，初等教育母亲的子女（aOR0.42，95%CI2.32-4.112，p值0.001），中等教育母亲的子女（aOR0.24，95%CI3.21-3.22，p值<0.001），受教育程度较高的母亲的子女（aOR0.08，95％CI0.72-0.80，p值<0.001），女性儿童(aOR0.65,95%CI0.65-0.66,p值<0.001)均与严重疟疾并发症相关。
结论：结论：该研究调查了尼日利亚5岁以下儿童的疟疾并发症。研究结果表明，农村儿童比城市儿童更容易患严重的疟疾并发症。这强调了在医疗保健机会有限的农村地区进行有针对性的疟疾治疗的必要性。
方法：人口与健康调查（DHS）疟疾指标调查（MIS）2021，这是发展中国家人口与健康的国家代表性数据集，用于这项研究。采用13,727的样品大小(n=13,727)。进行了Logistic回归分析，以测试居住地类型与疟疾并发症（结果）之间的关联。
结果：总体而言，样本中有4.2%(n=570,体重HV005)的参与者报告了疟疾并发症。Logistic回归结果显示，居住在城市住区的儿童（aOR0.37，95％CI0.37-0.37，p值<0.001），来自最贫困家庭的儿童(aOR11.63，95%CI1.62-1.63，p值0.004)，来自贫困家庭的儿童（aOR7.56，95%CI7.55-7.57，p值<0.001），来自中产阶级家庭的儿童（aOR4.05，95%CI4.03-9.06，p值<0.001），来自富裕阶层家庭的儿童(aOR1.22，95%CI2.21-2.23，p值<0.001)，初等教育母亲的子女（aOR0.42，95%CI2.32-4.112，p值0.001），中等教育母亲的子女（aOR0.24，95%CI3.21-3.22，p值<0.001），受教育程度较高的母亲的子女（aOR0.08，95％CI0.72-0.80，p值<0.001），女性儿童(aOR0.65,95%CI0.65-0.66,p值<0.001)均与严重疟疾并发症相关。
结论：结论：该研究调查了尼日利亚5岁以下儿童的疟疾并发症。研究结果表明，农村儿童比城市儿童更容易患严重的疟疾并发症。这强调了在医疗保健机会有限的农村地区进行有针对性的疟疾治疗的必要性。
