Abstract:
Adenoid cystic carcinoma is a rare malignant tumor that primarily occurs in the salivary glands. There are few reports of sublingual gland adenoid cystic carcinoma with lung metastases on which 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG-PET/CT) was performed. We report the case of a 57-year-old Japanese woman with an adenoid cystic carcinoma of the sublingual gland with lung metastases in whom the FDG uptake of the lung metastasis was low despite high FDG uptake in the primary lesion. The pathological examination revealed that solid components were more visible and the Ki-67 index was more positive in the primary lesion compared to the metastatic lesion. We speculate that differences in tumor growth ability might have resulted in the differences in FDG uptake. This case demonstrates that significant differences might occur in the FDG uptake between primary and metastatic tumors.
摘要:
腺样囊性癌是一种罕见的恶性肿瘤,主要发生在唾液腺。很少有关于舌下腺腺样囊性癌伴肺转移的报道,在其上进行了18F-氟脱氧葡萄糖正电子发射断层扫描/计算机断层扫描(18F-FDG-PET/CT)。我们报道了一名57岁的日本妇女,患有舌下腺腺样囊性癌并有肺转移,尽管原发病灶的FDG摄取较高,但肺转移的FDG摄取较低。病理检查显示,与转移灶相比,原发灶的实体成分更明显,Ki-67指数更阳性。我们推测,肿瘤生长能力的差异可能导致FDG摄取的差异。这种情况表明,原发性和转移性肿瘤之间的FDG摄取可能存在显着差异。