PDF(Pubmed)
Abstract：
UNASSIGNED: The paper describes the first documentary evidence of intestinal histoplasmosis in Indian goats.
UNASSIGNED: A goat flock in delta region of Tamil Nadu with a report of mortality of eight animals with the history of inappetence, constipation, tenesmus and hematochezia. Three goat carcasses were presented for necropsy.
UNASSIGNED: Postmortem examination showed mesenteric lymphadenomegaly with greyish yellow viscous contents. Ileum contained scattered dark brownish tubular concretions inside the lumen. Colon and caecum had scattered firm serosal and mucosal nodules with caseous exudate. Lumen contained viscous haemorrhagic content. Mucosa of the colon showed numerous tiny ulcers. Urinary bladder serosa showed a focal firm nodule with caseous exudate and irregular firm mass. Microscopically, lung revealed oval inclusions with clear halo in pulmonary macrophages. Caecum and colon showed ulcers with necrotic core. Necrotic border showed multinucleated giant cells and oval bodies with clear halo. Mesenteric lymph node and urinary bladder revealed pyogranulomatous inflammation with aggregation of macrophages filled with numerous tiny inclusions. Periodic acid-Schiff and Grocott\'s methanamine silver staining techniques and morphological features of the inclusion confirmed it as Histoplasma capsulatum. The case showed a resemblance with human colonic histoplasmosis.
UNASSIGNED: This report documents the first incidence of intestinal histoplasmosis in goats. Interestingly, the intestinal form of histoplasmosis is considered to be common in humans and it showed similarity with human disease in goats based on the gross and microscopic lesions.
UNASSIGNED: A goat flock in delta region of Tamil Nadu with a report of mortality of eight animals with the history of inappetence, constipation, tenesmus and hematochezia. Three goat carcasses were presented for necropsy.
UNASSIGNED: Postmortem examination showed mesenteric lymphadenomegaly with greyish yellow viscous contents. Ileum contained scattered dark brownish tubular concretions inside the lumen. Colon and caecum had scattered firm serosal and mucosal nodules with caseous exudate. Lumen contained viscous haemorrhagic content. Mucosa of the colon showed numerous tiny ulcers. Urinary bladder serosa showed a focal firm nodule with caseous exudate and irregular firm mass. Microscopically, lung revealed oval inclusions with clear halo in pulmonary macrophages. Caecum and colon showed ulcers with necrotic core. Necrotic border showed multinucleated giant cells and oval bodies with clear halo. Mesenteric lymph node and urinary bladder revealed pyogranulomatous inflammation with aggregation of macrophages filled with numerous tiny inclusions. Periodic acid-Schiff and Grocott\'s methanamine silver staining techniques and morphological features of the inclusion confirmed it as Histoplasma capsulatum. The case showed a resemblance with human colonic histoplasmosis.
UNASSIGNED: This report documents the first incidence of intestinal histoplasmosis in goats. Interestingly, the intestinal form of histoplasmosis is considered to be common in humans and it showed similarity with human disease in goats based on the gross and microscopic lesions.
摘要：
■本文描述了印度山羊肠组织胞浆菌病的第一个文献证据。
■泰米尔纳德邦三角洲地区的一只羊群，据报道有八只食欲不振的动物死亡，便秘,急速重和便血。提出了三只山羊尸体进行尸检。
■尸检显示肠系膜淋巴结肿大，含灰黄色粘稠内容物。回肠在管腔内含有分散的深褐色管状结石。结肠和盲肠有散布的坚固的浆膜和粘膜结节，并伴有干酪样渗出液。管腔含有粘稠的出血内容物。结肠粘膜显示许多微小溃疡。膀胱浆膜显示局灶性硬结节，有干酪样渗出物和不规则的硬肿块。微观上,肺显示椭圆形包涵体，肺巨噬细胞中有清晰的光环。盲肠和结肠显示溃疡伴坏死核心。坏死边界显示多核巨细胞和卵圆形体，有明显的光环。肠系膜淋巴结和膀胱显示脓性肉芽肿性炎症，巨噬细胞聚集，充满许多微小包涵体。高碘酸-希夫和格罗科特的甲胺银染色技术和包涵体的形态特征证实它是组织胞浆。该病例与人类结肠组织胞浆菌病相似。
■本报告记录了山羊肠组织胞浆菌病的首次发病率。有趣的是,组织胞浆菌病的肠道形式被认为在人类中很常见，并且基于总体和微观病变，它与山羊的人类疾病相似。
■泰米尔纳德邦三角洲地区的一只羊群，据报道有八只食欲不振的动物死亡，便秘,急速重和便血。提出了三只山羊尸体进行尸检。
■尸检显示肠系膜淋巴结肿大，含灰黄色粘稠内容物。回肠在管腔内含有分散的深褐色管状结石。结肠和盲肠有散布的坚固的浆膜和粘膜结节，并伴有干酪样渗出液。管腔含有粘稠的出血内容物。结肠粘膜显示许多微小溃疡。膀胱浆膜显示局灶性硬结节，有干酪样渗出物和不规则的硬肿块。微观上,肺显示椭圆形包涵体，肺巨噬细胞中有清晰的光环。盲肠和结肠显示溃疡伴坏死核心。坏死边界显示多核巨细胞和卵圆形体，有明显的光环。肠系膜淋巴结和膀胱显示脓性肉芽肿性炎症，巨噬细胞聚集，充满许多微小包涵体。高碘酸-希夫和格罗科特的甲胺银染色技术和包涵体的形态特征证实它是组织胞浆。该病例与人类结肠组织胞浆菌病相似。
■本报告记录了山羊肠组织胞浆菌病的首次发病率。有趣的是,组织胞浆菌病的肠道形式被认为在人类中很常见，并且基于总体和微观病变，它与山羊的人类疾病相似。
