PDF(Pubmed)
Abstract：
UNASSIGNED: Premature ovarian insufficiency (POI) seriously affects the reproductive health of women. Several studies have been conducted to show that POI appears to be associated with psychological and psychosocial problems, but whether POI increases the risk of mental health problems has not been identified. Therefore, this meta-analysis provides a preliminary systematic assessment of the studies published to date on the impact of POI on women\'s mental health.
UNASSIGNED: We implemented a systematic search for studies on this topic up to October 2022. Pooled odds ratios (ORs) and 95% confident intervals (CIs) of prevalence were used to assess the impacts of POI on various psychological factors, and the publication bias was assessed by Egger\'s test.
UNASSIGNED: A total of 15 articles comprising 5820 participants were included in this meta-analysis. POI was found to be related to higher risk of 13 psychological and psychosocial problems identified and classified into 3 domains: depression (OR = 1.61; 95% CI: 1.11-2.33), anxiety (OR = 3.74; 95% CI: 1.78-7.87), and poor life quality (OR = 2.55, 95% CI: 1.63-3.97).
UNASSIGNED: This meta-analysis reveals that women with POI have an increased risk of depression, anxiety, and poor life quality. The marital status of POI may be a possible influencing factor for depression, meaning that the unmarried status in POI is at high risk of psychological and psychosocial problems. We should pay attention to the mental health of women with POI who were unmarried.
UNASSIGNED: We implemented a systematic search for studies on this topic up to October 2022. Pooled odds ratios (ORs) and 95% confident intervals (CIs) of prevalence were used to assess the impacts of POI on various psychological factors, and the publication bias was assessed by Egger\'s test.
UNASSIGNED: A total of 15 articles comprising 5820 participants were included in this meta-analysis. POI was found to be related to higher risk of 13 psychological and psychosocial problems identified and classified into 3 domains: depression (OR = 1.61; 95% CI: 1.11-2.33), anxiety (OR = 3.74; 95% CI: 1.78-7.87), and poor life quality (OR = 2.55, 95% CI: 1.63-3.97).
UNASSIGNED: This meta-analysis reveals that women with POI have an increased risk of depression, anxiety, and poor life quality. The marital status of POI may be a possible influencing factor for depression, meaning that the unmarried status in POI is at high risk of psychological and psychosocial problems. We should pay attention to the mental health of women with POI who were unmarried.
摘要：
■过早卵巢功能不全（POI）严重影响女性的生殖健康。一些研究表明，POI似乎与心理和社会心理问题有关，但是POI是否会增加心理健康问题的风险尚未确定。因此,本荟萃分析对迄今为止发表的关于POI对女性心理健康影响的研究进行了初步系统评估.
■我们在2022年10月之前对有关该主题的研究进行了系统搜索。合并的优势比（ORs）和95％的置信区间（CIs）的患病率被用来评估POI对各种心理因素的影响，发表偏倚通过Egger检验进行评估。
■本荟萃分析共纳入15篇文章，包括5820名参与者。POI被发现与13个心理和心理社会问题的高风险相关，并分为3个领域：抑郁症（OR=1.61;95％CI：1.11-2.33），焦虑（OR=3.74；95%CI：1.78-7.87），生活质量差(OR=2.55,95%CI:1.63~3.97)。
这项荟萃分析显示，患有POI的女性患抑郁症的风险增加，焦虑,生活质量差。POI的婚姻状况可能是抑郁症的影响因素,这意味着POI中的未婚状态是心理和社会心理问题的高风险。我们应该关注未婚女性POI的心理健康。
■我们在2022年10月之前对有关该主题的研究进行了系统搜索。合并的优势比（ORs）和95％的置信区间（CIs）的患病率被用来评估POI对各种心理因素的影响，发表偏倚通过Egger检验进行评估。
■本荟萃分析共纳入15篇文章，包括5820名参与者。POI被发现与13个心理和心理社会问题的高风险相关，并分为3个领域：抑郁症（OR=1.61;95％CI：1.11-2.33），焦虑（OR=3.74；95%CI：1.78-7.87），生活质量差(OR=2.55,95%CI:1.63~3.97)。
这项荟萃分析显示，患有POI的女性患抑郁症的风险增加，焦虑,生活质量差。POI的婚姻状况可能是抑郁症的影响因素,这意味着POI中的未婚状态是心理和社会心理问题的高风险。我们应该关注未婚女性POI的心理健康。
